Protein Alignment Cdk5 and cdk7

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_998126.2
• Gene: cdk7 / 405897
• ZFINID: ZDB-GENE-010320-2
• Length: 345
• Species: Danio rerio
• Alignment Length: 293
• Identity: 125/293 - (42%)
• Similarity: 188/293 - (64%)
• Gaps: 11/293 - (3%)

  Fly     2 QKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRL---DEDDEGVPSSALREICLLKELKHKNI 63
            ::|:|::.:|||.:.||:|.|::.|..|||:|::::   .|..:|:..:|||||.||:||.|.||
Zfish    10 KRYEKLDFLGEGQFATVYKARDKTTNTIVAIKKIKVGHRTEAKDGINRTALREIKLLQELSHPNI 74

  Fly    64 VRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLK 128
            :.|:|.......::|||::.:.||:......:..:..|..::::|..|:||.:.|:|.:||||||
Zfish    75 IGLLDAFGHKSNISLVFDYMETDLEVIIKDTSLVLTPANIKAYILMTLQGLEYMHNHWILHRDLK 139

  Fly   129 PQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILA 193
            |.|||:::||.|||||||||:|||.|.:.|:.:|||.|||.|::||||::|...:|||:.|||||
Zfish   140 PNNLLLDENGVLKLADFGLAKAFGSPNRVYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILA 204

  Fly   194 ELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPRLNSK 258
            ||. ...|...|...||||.|||..||||.::.|||:|.|.|||:...||.    :.|....::.
Zfish   205 ELL-LRVPFLAGDSDLDQLTKIFEALGTPTDEIWPGMSSLPDYVSFKPFPG----TPLEHIFSAA 264

  Fly   259 GRDLLQ---KLLICRPNQRISAEAAMQHPYFTD 288
            |.|||:   .|....|..|.:|..|::..||::
Zfish   265 GDDLLELLRGLFTYNPCSRTTAMQALKMKYFSN 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	123/288 (43%)
cdk7	NP_998126.2	STKc_CDK7	11..308	CDD:270833	125/292 (43%)