Protein Alignment Cdk5 and Cdk4

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_477196.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 130/294 - (44%)
• Similarity: 173/294 - (58%)
• Gaps: 18/294 - (6%)

  Fly     4 YDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKEL---KHKNIVR 65
            |.::..||||.||||::.|:..|..|||||:||:..::.|||.|.||||.|||:|   .|.|||:
  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNENGVPMSTLREISLLKQLNASNHANIVK 90

  Fly    66 LIDV---LHSDKKL--TLVFEHCDQDLKKYFDSL-NGEIDMAVCRSFMLQLLRGLAFCHSHNVLH 124
            |.:|   |..|.:|  .|||||.:|||....|.| ...:.....:....:||.|:.|.|||.::|
  Fly    91 LYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSHRIIH 155

  Fly   125 RDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAG 189
            |||||||||::..|.||:||||||:.:|..:|..|. |||||||.|:||. |:.|.:::|:|||.
  Fly   156 RDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKLTSV-VVTLWYRAPEVLL-AQPYNSTVDIWSAA 218

  Fly   190 CILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPA--ITSWSQLV 252
            ||:.|:.:. |.||||:...:||.:||.:.|.|.|..||....    |||..||.  ........
  Fly   219 CIIFEMFNR-RALFPGTSEKNQLDRIFELTGRPTEQQWPQTIS----VALEHFPQRHPKRPKDFC 278

  Fly   253 PRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYF 286
            |.|.....|||.|:|....:.|.||.|.::|.||
  Fly   279 PHLCKYADDLLNKMLSYDLHLRPSALACLEHDYF 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	128/292 (44%)
Cdk4	NP_477196.1	STKc_CDK4_6_like	26..312	CDD:270831	128/292 (44%)