Protein Alignment Cdk5 and Cdk2

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: XP_562342.4
• Gene: Cdk2 / 3291042
• VectorBaseID: AGAMI1_009397
• Length: 309
• Species: Anopheles gambiae
• Alignment Length: 299
• Identity: 152/299 - (50%)
• Similarity: 197/299 - (65%)
• Gaps: 17/299 - (5%)

  Fly     1 MQK---YDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKN 62
            ||:   ||:::||||||||.|:|.::..|...|||||:|||.:.||:||:|:|||.|||:|||.:
Mosquito    13 MQRVGVYDRVDKIGEGTYGVVYKAKDIRTQNYVALKRIRLDNETEGIPSTAMREISLLKDLKHHS 77

  Fly    63 IVRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDL 127
            ||.|.||:..|..:.:|||:.|.||||..|.........:.:|:|.|:|..:|:||.:.:|||||
Mosquito    78 IVELFDVVIIDASIYMVFEYLDMDLKKMLDRHKSSFTPMLVKSYMHQMLDAIAYCHLNRILHRDL 142

  Fly   128 KPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCIL 192
            |||||||::.|.:||||||||||...|::.|:.||||||||.|::|.|.|.|...:|.||.|||.
Mosquito   143 KPQNLLIDREGHIKLADFGLARAVNFPIRVYTHEVVTLWYRAPEILLGTKFYCVGVDTWSLGCIF 207

  Fly   193 AELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWS-QLVPRLN 256
            ||:. ..||||||...:|||.||||.:|||:|..||||||||||  ..|||   .|. |.:|  |
Mosquito   208 AEMI-LKRPLFPGDSEIDQLFKIFRQMGTPDETKWPGVSHLSDY--KESFP---YWEPQPLP--N 264

  Fly   257 SKGRDLLQKLLICR-----PNQRISAEAAMQHPYFTDSS 290
            ....||....|.|.     |.:|:|.::||.|.||.:.|
Mosquito   265 EMQHDLDAHTLFCELMHYDPTKRLSPKSAMSHSYFDNVS 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	147/291 (51%)
Cdk2	XP_562342.4	Protein Kinases, catalytic domain	19..299	CDD:473864	147/287 (51%)