Protein Alignment Cdk5 and Cdkl1

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001020292.1
• Gene: Cdkl1 / 314198
• RGDID: 1305080
• Length: 352
• Species: Rattus norvegicus
• Alignment Length: 288
• Identity: 114/288 - (39%)
• Similarity: 165/288 - (57%)
• Gaps: 3/288 - (1%)

  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVR 65
            |:||:|:.|||||:||.|||.|||||.:|||:||....|||..:...|||||.:||:|||.|:|.
  Rat     1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLVS 65

  Fly    66 LIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQ 130
            |::|....::|.||||:|...:....|.....:...:.::...|.|:.:.|||.||.:|||:||:
  Rat    66 LLEVFRRKRRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPE 130

  Fly   131 NLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAEL 195
            |:||.|:..:||.|||.||....|...|:..|.|.|||.|::|.|...|...:|:|:.||:.|||
  Rat   131 NILITKHSVIKLCDFGFARLLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAEL 195

  Fly   196 ADAGRPLFPGSDVLDQLMKIFRVLG--TPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPRLNSK 258
            . :|.||:||...:|||..|.:.||  .|.......::.....|.:|....:.:.....|.::..
  Rat   196 L-SGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVKIPDPEDMETLELKFPNISYS 259

  Fly   259 GRDLLQKLLICRPNQRISAEAAMQHPYF 286
            ....|:..|...|.:|::.|..:|||||
  Rat   260 ALGFLKGCLHMDPAERLTCEQLLQHPYF 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	111/284 (39%)
Cdkl1	NP_001020292.1	STKc_CDKL1_4	2..287	CDD:270837	111/285 (39%)
		[NKR]KIAxRE	45..51		2/5 (40%)