Protein Alignment Cdk5 and Pdik1l

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001101454.1
• Gene: Pdik1l / 313609
• RGDID: 1307476
• Length: 341
• Species: Rattus norvegicus
• Alignment Length: 355
• Identity: 93/355 - (26%)
• Similarity: 152/355 - (42%)
• Gaps: 90/355 - (25%)

  Fly     3 KYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELK--HKNIVR 65
            |||.:.::|.|:||.|::...|.|...||:|::|....:.  ...||||...|..:|  |.|::.
  Rat     7 KYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPEN--VELALREFWALSSIKSQHPNVIH 69

  Fly    66 LID-VLHSD---KKLT-------------------------------LVFEHCD-QDLKKYFDSL 94
            |.: :|..|   :|::                               .|.:.|| .|:.:|.  |
  Rat    70 LEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMDFCDGGDMNEYL--L 132

  Fly    95 NGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKN--------GELKLADFGLARAF 151
            :.:.:.....||||||...|||.|.:.::||||||.|:||:::        ..||:|||||::..
  Rat   133 SRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQSRLDTSDLEPTLKVADFGLSKVC 197

  Fly   152 GI-------PV---KCY-SAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPG 205
            ..       ||   ||: |....|.:|..|:|..|.  ||...|:::.|.|:..:.:  |..|..
  Rat   198 SASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGH--YTAKADIFALGIIIWAMLE--RITFID 258

  Fly   206 SDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAI---TSWSQLVP----RLNSKGRDLL 263
            ::...:|:..:...||.               .:|...|:   .....|:|    .:|.:.:.|:
  Rat   259 TETKKELLGSYVKQGTE---------------IVPVGEALLENPKMELLIPVKKKSMNGRMKQLI 308

  Fly   264 QKLLICRPNQRISA---EAAMQHPYFTDSS 290
            :::|...|..|..|   |..:....|.|||
  Rat   309 KEMLAANPQDRPDAFELELRLVQIAFKDSS 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	89/349 (26%)
Pdik1l	NP_001101454.1	STKc_PDIK1L	7..331	CDD:270879	89/346 (26%)