Protein Alignment Cdk5 and Cdk19

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001101104.1
• Gene: Cdk19 / 309804
• RGDID: 1305435
• Length: 501
• Species: Rattus norvegicus
• Alignment Length: 322
• Identity: 118/322 - (36%)
• Similarity: 177/322 - (54%)
• Gaps: 52/322 - (16%)

  Fly     9 KIGEGTYGTVFKGRNRDTME--IVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLIDVL- 70
            |:|.||||.|:|.|.:|..:  ..|||::    :..|:..||.|||.||:||||.|::.|..|.
  Rat    26 KVGRGTYGHVYKARRKDGKDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIALQKVFL 86

  Fly    71 -HSDKKLTLVFEHCDQDL-------------KKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHN 121
             |||:|:.|:|::.:.||             ||..     ::..::.:|.:.|:|.|:.:.|::.
  Rat    87 SHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPM-----QLPRSMVKSLLYQILDGIHYLHANW 146

  Fly   122 VLHRDLKPQNLLI----NKNGELKLADFGLARAFGIPVKCYS---AEVVTLWYRPPDVLFGAKLY 179
            ||||||||.|:|:    .:.|.:|:||.|.||.|..|:|..:   ..|||.|||.|::|.||:.|
  Rat   147 VLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHY 211

  Fly   180 TTSIDMWSAGCILAELADAGRPLF--PGSDVL-------DQLMKIFRVLGTPNEDSWPGVSHLSD 235
            |.:||:|:.|||.|||. ...|:|  ...|:.       |||.:||.|:|.|.:..|..:..:.:
  Rat   212 TKAIDIWAIGCIFAELL-TSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPE 275

  Fly   236 YVALPSFPAITSW--SQLVPRL-------NSKGRDLLQKLLICRPNQRISAEAAMQHPYFTD 288
            |..|......|::  |.|:..:       :||...||||||...|.:||::|.|:|.|||.:
  Rat   276 YPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQE 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	116/318 (36%)
Cdk19	NP_001101104.1	STKc_CDC2L6	18..335	CDD:270850	116/318 (36%)