Protein Alignment Cdk5 and cdk11

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_595739.1
• Gene: cdk11 / 2540799
• PomBaseID: SPBC18H10.15
• Length: 398
• Species: Schizosaccharomyces pombe
• Alignment Length: 296
• Identity: 130/296 - (43%)
• Similarity: 174/296 - (58%)
• Gaps: 17/296 - (5%)

  Fly     4 YDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLID 68
            |:.:|||.||:||.|::|.::.|..:||||:::.|.:..|.|.::||||..|..::|.|||.|..
pombe    74 YEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDNIVELEK 138

  Fly    69 VLHSD--KKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQN 131
            |:...  |.:.||.|..:.|||...|::..:...:..::.|||||...||.|.|..|||||||.|
pombe   139 VVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATAFMHHHWYLHRDLKPSN 203

  Fly   132 LLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELA 196
            ||:|..||:|||||||||....|....:..|||||||.|::|.||..|...|||||.|||.||:.
pombe   204 LLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMI 268

  Fly   197 DAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALP-----SFPAITSWSQL---VP 253
             ...|||.|...||||.|||.:||.|..:.||      .|..||     ..|.:.:.|::   :|
pombe   269 -TRTPLFSGKSELDQLYKIFNLLGYPTREEWP------QYFLLPYANKIKHPTVPTHSKIRTSIP 326

  Fly   254 RLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTDS 289
            .|.....|||.:||...|.:||||:.|::||||.:|
pombe   327 NLTGNAYDLLNRLLSLNPAKRISAKEALEHPYFYES 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	127/291 (44%)
cdk11	NP_595739.1	STKc_CDC2L1	68..359	CDD:173741	127/291 (44%)