Protein Alignment Cdk5 and pmk-1

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_501365.1
• Gene: pmk-1 / 191743
• WormBaseID: WBGene00004055
• Length: 377
• Species: Caenorhabditis elegans
• Alignment Length: 308
• Identity: 103/308 - (33%)
• Similarity: 160/308 - (51%)
• Gaps: 50/308 - (16%)

  Fly     4 YDKMEKIGEGTYGTV-------------FKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLL 55
            |..:..||.|.||||             .|..||....|:..:|             ..||:.||
 Worm    35 YINLTPIGTGAYGTVCAAECTRSGTRVAIKKFNRPFQSIIHARR-------------TYRELRLL 86

  Fly    56 KELKHKNIVRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMA-----------VCRSFMLQ 109
            :.:.|:||:.|:||...::.:..:     :|:  ||.|:....|::           ..:..:.|
 Worm    87 RCMCHENIIDLLDVFTPNENVNDI-----EDV--YFVSMLMGADLSNILKIQRLNDDHIQFLVYQ 144

  Fly   110 LLRGLAFCHSHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLF 174
            :||||.:.||.:::||||||.|:.:|::.|||:.||||||.....:..|   |.|.|||.|:::.
 Worm   145 ILRGLKYIHSADIIHRDLKPSNIAVNEDCELKILDFGLARQTDSEMTGY---VATRWYRAPEIML 206

  Fly   175 GAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVAL 239
            ....||.::|:||.|||||||. .|:.||||||.:|||.:|..|.|||:|:....:|.......:
 Worm   207 NWMHYTQTVDVWSVGCILAELI-TGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYI 270

  Fly   240 PSFPAIT--SWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPY 285
            .:.|.:|  .:.:|..:...:..|||:|:|...|::|.:|:.||:|.|
 Worm   271 RNLPKMTRRDFKRLFAQATPQAIDLLEKMLHLDPDRRPTAKEAMEHEY 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	103/308 (33%)
pmk-1	NP_501365.1	STKc_p38	19..361	CDD:143356	103/308 (33%)