Protein Alignment Cdk5 and Y38E10A.8

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_496691.3
• Gene: Y38E10A.8 / 189655
• WormBaseID: WBGene00012586
• Length: 289
• Species: Caenorhabditis elegans
• Alignment Length: 323
• Identity: 82/323 - (25%)
• Similarity: 137/323 - (42%)
• Gaps: 92/323 - (28%)

  Fly     3 KYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKEL-KHKNIVRL 66
            :||.::.:|:|::|.||:.:.::..|:.|:|  |||.|...:|.:| ||:..:..: :|...:..
 Worm    17 RYDVVDVLGQGSFGIVFQAQRKNDRELRAVK--RLDLDSATLPRAA-REVTTITSIGRHSGYIFF 78

  Fly    67 IDVLHSDKK------LTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFML------QLLRGLAFCHS 119
            .:|...:.|      :.:..|.|:|:..|  |.:.|. ..|..|.:||      ||...|...||
 Worm    79 DEVFWKEHKTGSAGHMYICMELCEQNTLK--DWIKGN-RTARSRPWMLMKDWIKQLACALDHLHS 140

  Fly   120 HNVLHRDLKPQNLLINKNGE---LKLADFGL-ARAF-GI-----------PVKCYSAEVVTLWYR 168
            :|.:||||||:|:...::.:   ||:.|||| .||. |:           ..:.::|...|..|.
 Worm   141 NNFIHRDLKPENVFFARDSQFKKLKIGDFGLTTRAIEGLKDWKQRTQSQEAGQNHTAGAGTPSYM 205

  Fly   169 PPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNED-------- 225
            .|:.:  ...|...:|:::.|.|.|||.                     ::.||:::
 Worm   206 APEQI--RNQYNEKVDIFALGLIAAELI---------------------IINTPSDEMGTNDIIR 247

  Fly   226 --SWPGVSHLSDYVALPSFP-AITSWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPY 285
              .||        :|...:| ||...|||. .:|              |..|.||.....||:
 Worm   248 SGQWP--------IAWQDYPDAIEFLSQLT-HMN--------------PTMRPSAVEVSMHPF 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	82/323 (25%)
Y38E10A.8	NP_496691.3	Protein Kinases, catalytic domain	14..285	CDD:473864	80/319 (25%)