Protein Alignment Cdk5 and Cdk14

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_035204.2
• Gene: Cdk14 / 18647
• MGIID: 894318
• Length: 469
• Species: Mus musculus
• Alignment Length: 291
• Identity: 149/291 - (51%)
• Similarity: 193/291 - (66%)
• Gaps: 10/291 - (3%)

  Fly     4 YDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLID 68
            |:|:||:|||:|.||:||:::...::||||.:||.| :||.|.:|:||..|||.|||.|||.|.|
Mouse   135 YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQE-EEGTPFTAIREASLLKGLKHANIVLLHD 198

  Fly    69 VLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLL 133
            ::|:.:.||||||:...||.:|.|...|.:.....:.|:.||||||::.|...:|||||||||||
Mouse   199 IIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLL 263

  Fly   134 INKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELADA 198
            |:..|||||||||||||..:|...||.|||||||||||||.|:..|:|.:|||..|||..|:..
Mouse   264 ISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQ- 327

  Fly   199 GRPLFPG-SDVLDQLMKIFRVLGTPNEDSWPGVSHL-----SDYVALPSFPAITSWSQLVPRLNS 257
            |...||| .|:.|||.:||.||||||||:||||..|     ..:....|.....:|::|  ...:
Mouse   328 GVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTVYSSKSLRQAWNKL--SYVN 390

  Fly   258 KGRDLLQKLLICRPNQRISAEAAMQHPYFTD 288
            ...||..|||.|.|..|:||:||:.|.||:|
Mouse   391 HAEDLASKLLQCSPKNRLSAQAALSHEYFSD 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	146/287 (51%)
Cdk14	NP_035204.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	103..133
		STKc_PFTAIRE1	129..431	CDD:143374	149/291 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	449..469