Protein Alignment Cdk5 and cdk-4

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_510256.1
• Gene: cdk-4 / 181472
• WormBaseID: WBGene00000406
• Length: 342
• Species: Caenorhabditis elegans
• Alignment Length: 238
• Identity: 54/238 - (22%)
• Similarity: 87/238 - (36%)
• Gaps: 75/238 - (31%)

  Fly   491 KDVLLVLKYVSNK--DVFM-------------RYHKAHLTRRLIL----DSS------------- 523
            ::.:||.::|.||  |.|:             ||.....|.|.||    ||.
 Worm   388 EEKILVYEFVPNKSLDQFLFEPTKKGQLDWAKRYKIIVGTARGILYLHHDSPLKIIHRDLKASNI 452

  Fly   524 -ADSEKEEDMVEWLREVGMPADYVNKLARMFQDIKVSEDLNTQFRSQTTR----HDAINIKILNA 583
             .|:|.|..:.::    ||        ||:|:        ..|.|:.|.|    |..|:.:.|..
 Worm   453 LLDAEMEPKVADF----GM--------ARIFR--------VDQSRADTRRVVGTHGYISPEYLMH 497

  Fly   584 GAWARGSERVSVS-LPLELEDYIPEVEEFYKKKHSGRKLQWY--HHMSNGTITFANNTGRFDLDV 645
            |.::..|:..|.. |.||:... .....|::...||:.|..|  .|..||:          .|::
 Worm   498 GQFSVKSDVYSFGVLVLEIISG-KRNSNFHETDESGKNLVTYAWRHWRNGS----------PLEL 551

  Fly   646 TTFQMAVLFAWNQRPNEKVSYENLRLATELPDPELRRTLWSLV 688
            ...::..    |.:.||.....::.|.....|||.|..|.:::
 Worm   552 VDSELEK----NYQSNEVFRCIHIALLCVQNDPEQRPNLSTII 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344
cdk-4	NP_510256.1	Protein Kinases, catalytic domain	38..324	CDD:473864