Protein Alignment Cdk5 and cdk-1

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001022747.1
• Gene: cdk-1 / 176374
• WormBaseID: WBGene00000405
• Length: 332
• Species: Caenorhabditis elegans
• Alignment Length: 306
• Identity: 148/306 - (48%)
• Similarity: 204/306 - (66%)
• Gaps: 20/306 - (6%)

  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVR 65
            :..:.|:|||||||||.|:||:||.|..:||:|::||:.:||||||:|:|||.|||||:|.|:|.
 Worm    19 LNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVG 83

  Fly    66 LIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGE--IDMAVCRSFMLQLLRGLAFCHSHNVLHRDLK 128
            |..|:..:.:|.|:||....|||:|.|.|..:  :.:...:|:..|:|:.:.|||...|:|||||
 Worm    84 LEAVIMQENRLFLIFEFLSFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLK 148

  Fly   129 PQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILA 193
            |||||::.||.:||||||||||.|||::.|:.||||||||.|::|.||:.|:..:||||.|||.|
 Worm   149 PQNLLVDNNGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFA 213

  Fly   194 ELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPR---- 254
            |:| ..:|||.|...:|:|.:||||||||.|..|.||..|.||.|  :||   .|.:...|
 Worm   214 EMA-TKKPLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKA--TFP---KWRENFLRDKFY 272

  Fly   255 --------LNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTDSSSS 292
                    |:.....||:.|||..|:.|::|:.|:.||||.:..:|
 Worm   273 DKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYFDNMDTS 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	145/296 (49%)
cdk-1	NP_001022747.1	STKc_CDK1_euk	21..312	CDD:270845	145/296 (49%)