Protein Alignment Cdk5 and cdk-14

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_490783.3
• Gene: cdk-14 / 171672
• WormBaseID: WBGene00022519
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 304
• Identity: 141/304 - (46%)
• Similarity: 187/304 - (61%)
• Gaps: 18/304 - (5%)

  Fly     4 YDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLID 68
            |.:::|:|||:|.||:|..::....|||||.::| :..||:|.:|:||..||:.|:|.|||.|.|
 Worm   216 YKRIDKLGEGSYATVYKCESKLDGSIVALKEIKL-QFQEGLPFTAIREASLLRNLRHANIVSLHD 279

  Fly    69 VLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLL 133
            :.:...:||.|||:...||.||.:.....:|....:..:.||||||.|||...:|||||||||||
 Worm   280 IFYQHHQLTFVFEYMKMDLSKYLEQNVYGLDSIDIKLLLFQLLRGLDFCHRKKILHRDLKPQNLL 344

  Fly   134 INKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELADA 198
            ::::|.|||||||||||..:|.:.||.|||||||||||||.|:..|:||:|||..|||.||:. .
 Worm   345 LDEDGVLKLADFGLARAKSVPSRTYSHEVVTLWYRPPDVLMGSTDYSTSLDMWGVGCIFAEIC-T 408

  Fly   199 GRPLFPGS------DVLDQLMKIFRVLGTPNEDSWPGVSHLSDYV--ALP-----SFPAITSWSQ 250
            |..|||||      ...|||..||.:.|||:|..||.|..|..|.  ..|     ||.|:   :.
 Worm   409 GAALFPGSKDSHYPGTKDQLDMIFSIRGTPDEKKWPEVKTLPGYTPELFPRYRELSFIAV---NP 470

  Fly   251 LVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTDSSSSGH 294
            :..::...|::||..||..||..|:||.:||.||||.......|
 Worm   471 MFTKILKTGQELLGMLLQLRPESRVSAASAMLHPYFASFPREVH 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	138/294 (47%)
cdk-14	NP_490783.3	Protein Kinases, catalytic domain	216..506	CDD:473864	138/294 (47%)