Protein Alignment Cdk5 and Csnk2a2

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_034104.1
• Gene: Csnk2a2 / 13000
• MGIID: 88547
• Length: 350
• Species: Mus musculus
• Alignment Length: 307
• Identity: 104/307 - (33%)
• Similarity: 163/307 - (53%)
• Gaps: 45/307 - (14%)

  Fly     4 YDKMEKIGEGTYGTVFKG---RNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELK-HKNIV 64
            |..:.|:|.|.|..||:.   .|.:.:.:..||.|:        .....||:.:|:.|: ..||:
Mouse    40 YQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVK--------KKKIKREVKILENLRGGTNII 96

  Fly    65 RLIDVLHS--DKKLTLVFEHCDQ-DLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRD 126
            :|||.:..  .|...||||:.:. |.|:.:..|. :.|:   |.:|.:||:.|.:|||..::|||
Mouse    97 KLIDTVKDPVSKTPALVFEYINNTDFKQLYQILT-DFDI---RFYMYELLKALDYCHSKGIMHRD 157

  Fly   127 LKPQNLLI-NKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGC 190
            :||.|::| ::..:|:|.|:|||. |..|.:.|:..|.:.:::.|::|...::|..|:||||.||
Mouse   158 VKPHNVMIDHQQKKLRLIDWGLAE-FYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGC 221

  Fly   191 ILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDY-VAL-PSFPAITS------ 247
            :||.:.....|.|.|.|..|||::|.:||||   |...|  :|..| :.| |.|..|..
Mouse   222 MLASMIFRKEPFFHGQDNYDQLVRIAKVLGT---DELYG--YLKKYHIDLDPHFNDILGQHSRKR 281

  Fly   248 WSQLVPRLNSKGR--------DLLQKLLICRPNQRISAEAAMQHPYF 286
            |...:   :|:.|        |||.|||.....||::|:.||:||||
Mouse   282 WENFI---HSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYF 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	102/305 (33%)
Csnk2a2	NP_034104.1	STKc_CK2_alpha	22..326	CDD:271034	104/307 (34%)