Protein Alignment Cdk5 and Cdk7

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: XP_312281.3
• Gene: Cdk7 / 1273315
• VectorBaseID: AGAMI1_011913
• Length: 343
• Species: Anopheles gambiae
• Alignment Length: 294
• Identity: 127/294 - (43%)
• Similarity: 184/294 - (62%)
• Gaps: 11/294 - (3%)

  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRL---DEDDEGVPSSALREICLLKELKHKN 62
            :.:|:|::.:|||.:.||:|.|:.:|.||||:|::::   :|..:|:..:|||||.||.||:|:|
Mosquito     7 LNRYEKIDFLGEGQFATVYKARDAETNEIVAVKKIKIGNREEAADGINRTALREIKLLHELQHEN 71

  Fly    63 IVRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDL 127
            |:.|:||......::|||:..|.||:.........:..|..:|:|:|.||||.:.|.|.:|||||
Mosquito    72 IIGLLDVFGHKSNVSLVFDFMDTDLEIIIKDPKIILTPANIKSYMIQTLRGLEYLHQHWILHRDL 136

  Fly   128 KPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCIL 192
            ||.||||:..|.||:.|||||:.||.|.:..:.:|||.|||.|::||||:.|...:|:|:.||||
Mosquito   137 KPNNLLISGTGVLKIGDFGLAKFFGSPNRINTNQVVTRWYRCPELLFGARQYGIGVDIWAVGCIL 201

  Fly   193 AELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPRLNS 257
            |||. ...|..||...||||.:||:|||||||.:||.|..|.|||....:|.|    .|.....:
Mosquito   202 AELL-LRVPFLPGESDLDQLTRIFQVLGTPNETNWPDVKSLPDYVQYKFYPPI----PLRDIFTA 261

  Fly   258 KGRDLLQ---KLLICRPNQRISAEAAMQHPYFTD 288
            ...||::   |:|...|..|.|...|::..||::
Mosquito   262 ASDDLIELANKMLALYPLHRCSCTEALKMAYFSN 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	125/288 (43%)
Cdk7	XP_312281.3	STKc_CDK7	9..306	CDD:270833	127/292 (43%)