Protein Alignment Cdk5 and Cdk7

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_034004.2
• Gene: Cdk7 / 12572
• MGIID: 102956
• Length: 346
• Species: Mus musculus
• Alignment Length: 293
• Identity: 125/293 - (42%)
• Similarity: 187/293 - (63%)
• Gaps: 11/293 - (3%)

  Fly     2 QKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRL---DEDDEGVPSSALREICLLKELKHKNI 63
            ::|:|::.:|||.:.||:|.|:::|.:|||:|:::|   .|..:|:..:|||||.||:||.|.||
Mouse    10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNI 74

  Fly    64 VRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLK 128
            :.|:|.......::|||:..:.||:......:..:..:..:::||..|:||.:.|.|.:||||||
Mouse    75 IGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLK 139

  Fly   129 PQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILA 193
            |.|||:::||.|||||||||::||.|.:.|:.:|||.|||.|::||||::|...:|||:.|||||
Mouse   140 PNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILA 204

  Fly   194 ELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPRLNSK 258
            ||. ...|..||...||||.:||..||||.|:.||.:..|.|||...|||.:......:    :.
Mouse   205 ELL-LRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGVPLQHIFI----AA 264

  Fly   259 GRDLL---QKLLICRPNQRISAEAAMQHPYFTD 288
            |.|||   |.|.:..|..|.:|..|::..||::
Mouse   265 GDDLLELIQGLFLFNPCTRTTASQALKTKYFSN 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	123/288 (43%)
Cdk7	NP_034004.2	STKc_CDK7	11..308	CDD:270833	125/292 (43%)