Protein Alignment Cdk5 and mapk4

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: XP_004910415.1
• Gene: mapk4 / 100498202
• XenbaseID: XB-GENE-484178
• Length: 577
• Species: Xenopus tropicalis
• Alignment Length: 321
• Identity: 122/321 - (38%)
• Similarity: 165/321 - (51%)
• Gaps: 46/321 - (14%)

  Fly     1 MQKYD------KMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELK 59
            |..||      ..:.:|.|..|.|....:......||:|::.:  .|......|||||.:::.|.
 Frog    11 MYGYDLGCHFVDFKPLGFGANGLVLSAVDSKNSRRVAVKKIAI--SDGRSMKHALREIKIIRRLN 73

  Fly    60 HKNIVRLIDV-------LHSD-KKLTLVF---EHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRG 113
            |.|||::..|       |..| .|..||:   ||.:.||.:..:  .|.:.....:.||.|||||
 Frog    74 HDNIVKVHAVLGPRGADLQGDILKYNLVYIVQEHMETDLAQLLE--QGPLTEDHAKLFMYQLLRG 136

  Fly   114 LAFCHSHNVLHRDLKPQNLLIN-KNGELKLADFGLARAFG--IPVKCYSAE-VVTLWYRPPDVLF 174
            |.:.||.|||||||||.|:.|: :...||:.||||||...  ...|.|.:| :||.|||.|.:|.
 Frog   137 LKYIHSTNVLHRDLKPANIFISTEELLLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLL 201

  Fly   175 GAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSD---- 235
            ....||.:||||:|||||||:. .||.||.||..|:|:..|.        |:.| |.|..|
 Frog   202 SPNNYTKAIDMWAAGCILAEML-TGRMLFAGSHELEQMQLIL--------DTIP-VIHEEDKEEL 256

  Fly   236 YVALPSFPAITSWS------QLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTDSS 290
            ...:||| ...||.      :|:|.:||:..|.|:|:|...|..|::||||:||||.:..|
 Frog   257 LKVMPSF-INASWEVRKPLRKLLPEMNSEAIDFLEKILTFNPMDRLTAEAALQHPYMSPYS 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	119/313 (38%)
mapk4	XP_004910415.1	STKc_MAPK4_6	14..351	CDD:143359	121/318 (38%)