Protein Alignment Cdk5 and cilk1

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: XP_002934912.3
• Gene: cilk1 / 100498050
• XenbaseID: XB-GENE-985841
• Length: 623
• Species: Xenopus tropicalis
• Alignment Length: 305
• Identity: 107/305 - (35%)
• Similarity: 173/305 - (56%)
• Gaps: 26/305 - (8%)

  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVR-----LDEDDEGVPSSALREICLLKELKH 60
            |.:|..::::|:||||:|..||:.::.|:||:|:::     .||      ...|||:..||:|.|
 Frog     1 MNRYTTVKQLGDGTYGSVILGRSVESGELVAIKKMKRKFYSWDE------CMNLREVKSLKKLNH 59

  Fly    61 KNIVRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHR 125
            .|:::|.:|:..:.:|..|||:..::|.:.....|.....::.|:.|.|:|:|||:.|.:...||
 Frog    60 ANVIKLKEVIRENNQLYFVFEYMKENLYQLMKDRNKLFPESIIRNIMYQILQGLAYIHKYGFFHR 124

  Fly   126 DLKPQNLLINKNGELKLADFGLAR-AFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAG 189
            ||||:|||......:|:||||||| ....|.  |:..|.|.|||.|:||..|..|.:.||:|:.|
 Frog   125 DLKPENLLCMGPELVKIADFGLARETRSRPP--YTDYVSTRWYRAPEVLLRATNYNSPIDIWAVG 187

  Fly   190 CILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYV------ALPSFPAITSW 248
            ||:||:... |||||||..:|.:.||.:|||||.::.|.....|:..:      .:||     :.
 Frog   188 CIMAEIYTL-RPLFPGSSEVDTIFKICQVLGTPKKNDWFEGFQLASAMNFRWAHCVPS-----NL 246

  Fly   249 SQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTDSSSSG 293
            ..|:|...:.|..:::.:|...|.:|.:|..|:::.||....:.|
 Frog   247 KTLIPNACADGIQVMRDMLQWDPKKRPTASQALRYSYFQVGQTLG 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	103/294 (35%)
cilk1	XP_002934912.3	STKc_MAK_like	4..284	CDD:270824	103/293 (35%)