Protein Alignment Khc-73 and AT5G06670

DIOPT Version :10

• Sequence 1: NP_001261000.1
• Gene: Khc-73 / 36718
• FlyBaseID: FBgn0019968
• Length: 1957
• Species: Drosophila melanogaster
• Sequence 2: NP_196285.5
• Gene: AT5G06670 / 830555
• AraportID: AT5G06670
• Length: 986
• Species: Arabidopsis thaliana
• Alignment Length: 1109
• Identity: 284/1109 - (25%)
• Similarity: 448/1109 - (40%)
• Gaps: 327/1109 - (29%)

  Fly     2 ASDKIKVAVRVRPFNRREIELDTKCIVEMEKQQTILQNPPPLEKIERKQPKTFAFDHCFYSLNPE 66
            :.:.:.|.||.||.:.|||....: |......:||::|       |..|...:|:|..|   .|.
plant    63 SKENVTVTVRFRPLSPREIRKGEE-IAWYADGETIVRN-------ENNQSIAYAYDRVF---GPT 116

  Fly    67 DENFASQETVFDCVGRGILDNAFQGYN---------ACIFAYGQTGSGKSYTMMGTQESKGIIPR 122
                .:...|:|...:.:::.|..|.|         ..|||||.|.|||::||.|.|.|.||||.
plant   117 ----TTTRNVYDVAAQHVVNGAMAGVNVTLSVNSTTGTIFAYGVTSSGKTHTMHGNQRSPGIIPL 177

  Fly   123 LCDQLFSAIANKSTPELMYKVEVSYMEIYNEKVHDLLDPKPNKQSLKVREHNVMGPYVDGLSQLA 187
            .....||.|  :.||...:.:.|||.|||||.|:|||:|.  .|:|::|| :..|.|::|:.:..
plant   178 AVKDAFSII--QETPRREFLLRVSYFEIYNEVVNDLLNPA--GQNLRIRE-DEQGTYIEGIKEEV 237

  Fly   188 VTSYQDIDNLMTEGNKSRTVAATNMNAESSRSHAVFSVVL-TQILTDQATGVSGEKVSRMSLVDL 251
            |.|...:.:|:..|.:.|.:.:|:.|..|||||.:|::.: :..|.|...| ....:|:::|:||
plant   238 VLSPAHVLSLIAAGEEHRHIGSTSFNLLSSRSHTMFTLTIESSPLGDNNEG-GAVHLSQLNLIDL 301

  Fly   252 AGSERAVKTGAVGDRLKEGSNINKSLTTLGLVISKLADQSNGKKSGNDKFVPYRDSVLTWLLKDN 316
            ||||.: |....|.|.||||.|||||.|||.|||||.|:       ....||||||.||.||:.:
plant   302 AGSESS-KAETSGLRRKEGSYINKSLLTLGTVISKLTDR-------RASHVPYRDSKLTRLLESS 358

  Fly   317 LGGNSRTVMVATISPSADNYEETLSTLRYADRAKRIVNHAVVNE--DPNARI------IRELRHE 373
            |.|:.|..::.|::|::.|.|||.:||::|.|||.|...|..|:  |..:.|      ||:|:.|
plant   359 LSGHGRVSLICTVTPASSNSEETHNTLKFAHRAKHIEIQAAQNKIIDEKSLIKKYQYEIRQLKEE 423

  Fly   374 VETLR------SMLKHATGSPVGDV--QDKLAESEN----LMKQISQTWEEKLVKTERIQNERQQ 426
            :|.|:      |.||..:|..:..|  :.||.|.|:    |:.:|     ::|.|...:.|:..|
plant   424 LEQLKQGIKPVSQLKDISGDDIDIVLLKQKLEEEEDAKAALLSRI-----QRLTKLILVSNKTPQ 483

  Fly   427 ALEKMGISVQASGIKVEKNKYYLVNLNADP----SLNELLVYYL--KDRTLIGGRTISGQQPDIQ 485
            ...                    .:..|||    |..|..:.||  |.|.|.....:     ::.
plant   484 TSR--------------------FSYRADPRRRHSFGEEELAYLPHKRRDLTDDENL-----ELY 523

  Fly   486 LSGLGIQPEHCVITIEDSGLYMEPVQGARCFVNGSAAVEKTPLQNG----------DRILWGNHH 540
            :|..| .||    .|:|:            |:.     ||...::|          |..|.|:..
plant   524 VSREG-TPE----IIDDA------------FIE-----EKKTRKHGLLNWLKIKKKDSSLGGSSL 566

  Fly   541 FFRVNSPKSNNTSMCASEPQ-------TPAQLIDYNFARDEIMQ-------NELSNDPIQTAIAR 591
            ..:.::.|||:|   .|.||       |.::|.:.:...|:|::       :|.|...|:|...|
plant   567 SDKSSAVKSNST---PSTPQGEGSDFHTESRLSEGSALADQIIETMENREAHEDSFHEIETPETR 628

  Fly   592 LERQHEEDKQVALEKQRQEYERQFQQLRN--ILSPSTPYAP------------------------ 630
            ::.  .:..::..|:|:...|...||.|:  :||.....||
plant   629 IKM--IDQMEILREQQKTLSEEMAQQSRSFKLLSEEAAKAPQNEEIKAEIINLNGDIKAKNDQIA 691

  Fly   631 ----------YAPYDPLRMGKITPNTPTSQMRVEKWAQERDEMFRRSLGQLKTDIMRA-NSLVQE 684
                      .|.:|.|....|.  ...|:||    ||..::.|       :.::..| |.::|
plant   692 TLGKQILDFVIASHDELDKSDIV--QAVSEMR----AQLNEKCF-------ELEVKAADNRIIQ- 742

  Fly   685 ANFLAEEMEKKTKFSVTLQIPPANL-------------------------SPNRRRGAFVSEPAI 724
                 |::.:||.|...||...|||                         |||:.....:.
plant   743 -----EQLTEKTSFCEDLQEEVANLKQQLSDALELGDINSVTCHMQQSSQSPNKNEEKVIE---- 798

  Fly   725 LVKRTNSGSQIWTMEKLENKLIDMREMYQEHKERVLNGLDEDNAKPQDPFYESQENHNLIGVANI 789
                    :|.:.:|:|:.|..::.|:.::        |:..|.|..:   ||.....|...|.|
plant   799 --------AQAFEIEELKLKAAELSELNEQ--------LEIRNKKLAE---ESSYAKELASAAAI 844

  Fly   790 FLEVLFHDVKLDYHTPIISQQGEVAGRLQVEIERIAGQMPQDRMCESVSESSGDSRDEYDDPVDP 854
            .|:.|..::                .||....||:|..:      .:|.:||      ...|...
plant   845 ELKALSEEI----------------ARLMNHNERLAADL------AAVQKSS------VTTPQGK 881

  Fly   855 TSNQITCRVTIKCASGLPLSLSNFVFCQYTFWGHQEMVVPVINAESTAHDQNMVFKFEHTQDFTV 919
            |.|                 |.|         |.:|.|      ......:|.:.:.:.    .:
plant   882 TGN-----------------LRN---------GRRESV------SKRKEQENSLMELKR----EL 910

  Fly   920 TINEEFLEHCIEGALSIEVWGHRSAGFSKTKGWEVEQQQAKARSLVDRWAELSRKIELWVEIHEL 984
            |:::| .|...|.||..::  .|.|...:|    ||:.:.:...|.:..|      .:|..:.:|
plant   911 TVSKE-REVSFEAALIEKI--QREAELQRT----VEESKQREAYLENELA------NMWGLVAKL 962

  Fly   985 NDNG 988
            ...|
plant   963 RSQG 966

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc-73	NP_001261000.1	KISc_KIF1A_KIF1B	4..359	CDD:276816	138/364 (38%)
		Kinesin_assoc	356..468	CDD:465047	32/137 (23%)
		FHA_KIF13	446..547	CDD:438758	23/116 (20%)
		KIF1B	741..786	CDD:463574	9/44 (20%)
		DUF3694	989..1243	CDD:463599	284/1109 (26%)
		CAP_GLY	1785..1850	CDD:460154
AT5G06670	NP_196285.5	KISc_CENP_E	66..394	CDD:276825	136/356 (38%)
		Smc	<638..>953	CDD:440809	79/427 (19%)