Protein Alignment Khc-73 and kif1c

DIOPT Version :10

• Sequence 1: NP_001261000.1
• Gene: Khc-73 / 36718
• FlyBaseID: FBgn0019968
• Length: 1957
• Species: Drosophila melanogaster
• Sequence 2: XP_031755447.1
• Gene: kif1c / 779557
• XenbaseID: XB-GENE-997155
• Length: 1105
• Species: Xenopus tropicalis
• Alignment Length: 989
• Identity: 376/989 - (38%)
• Similarity: 532/989 - (53%)
• Gaps: 205/989 - (20%)

  Fly     1 MASDKIKVAVRVRPFNRREIELDTKCIVEMEKQQTILQNPPPLEKIERKQP----KTFAFDHCFY 61
            ||...:||||||||||.|||..|.||:::|:...|.:.||        |||    |.|.||:.::
 Frog     1 MAGASVKVAVRVRPFNSREIAHDAKCVIQMQGNTTCISNP--------KQPKDSAKNFTFDYSYW 57

  Fly    62 S-LNPEDENFASQETVFDCVGRGILDNAFQGYNACIFAYGQTGSGKSYTMMGTQESK--GIIPRL 123
            | ...||.|||||..|:..:|..:|.:||:|||.||||||||||||||||||..||:  ||||:|
 Frog    58 SHTTAEDPNFASQCQVYKDIGEEMLLHAFEGYNVCIFAYGQTGSGKSYTMMGKPESEQHGIIPQL 122

  Fly   124 CDQLFSAIANKSTPELMYKVEVSYMEIYNEKVHDLLDPKPNKQSLKVREHNVMGPYVDGLSQLAV 188
            |:.||:.::...:|:|...|||||||||.|:|.|||:|| :|.:|:||||.:|||||:.||:|||
 Frog   123 CEDLFARVSANRSPDLSCSVEVSYMEIYCERVRDLLNPK-SKGNLRVREHPIMGPYVEDLSKLAV 186

  Fly   189 TSYQDIDNLMTEGNKSRTVAATNMNAESSRSHAVFSVVLTQILTDQATGVSGEKVSRMSLVDLAG 253
            |||.||.:||..|||:|||||||||..||||||||::|.||...|:.|.:..||||::|||||||
 Frog   187 TSYHDIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQKRHDEMTNLDTEKVSKISLVDLAG 251

  Fly   254 SERAVKTGAVGDRLKEGSNINKSLTTLGLVISKLADQSNGKKSGNDKFVPYRDSVLTWLLKDNLG 318
            ||||..|||.|.|||||:||||||||||.|||.||:..|.||..:  |:|||||.||||||:|||
 Frog   252 SERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMQNKKKKSD--FIPYRDSALTWLLKENLG 314

  Fly   319 GNSRTVMVATISPSADNYEETLSTLRYADRAKRIVNHAVVNEDPNARIIRELRHEVETLRSMLKH 383
            |||||.|:|.:||:..||||||||||||||||:|..:||:|||||||:||||:.||..||.:| :
 Frog   315 GNSRTAMIAALSPADINYEETLSTLRYADRAKQIKCNAVINEDPNARLIRELKEEVARLRQLL-Y 378

  Fly   384 ATG--------------------SPVG-----------------------------------DVQ 393
            :.|                    :||.                                   :..
 Frog   379 SQGLEDIVIDDSASAPHPPSPAAAPVSPPPLPGSLAPLASPTQNGQSEPFPEGEDAAEICTEEAM 443

  Fly   394 DKLAESENLMKQISQTWEEKLVKTERIQNERQQALEKMGISVQASGIKV----EKNKYYLVNLNA 454
            ::|.|:|.::.::::||||||.|||.::.||:..|.:||::|:..|..|    .|...:|||||.
 Frog   444 ERLQETEKIIAELNETWEEKLRKTEALRTEREALLAEMGVAVREDGGTVGVFSPKKIPHLVNLNE 508

  Fly   455 DPSLNELLVYYLKDRTLIGGRTISGQ-QPDIQLSGLGIQPEHCVITIE--DSG---LYMEPVQGA 513
            ||.::|.|:|::|:     |.|..|| :.||:|||..|:.:||:...:  .||   :.:||.:||
 Frog   509 DPLMSECLLYHIKE-----GITRVGQVEVDIKLSGQFIKEQHCLFHCDTNPSGEVIVTLEPCEGA 568

  Fly   514 RCFVNGSAAVEKTPLQNGDRILWGNHHFFRVNSPK----SNNTSMCASEPQTPAQLIDYNFARDE 574
            ..:|||....:...|::|.||:.|.:|.||.|.|:    ....|..|.|  .|::.:|:|||:.|
 Frog   569 ETYVNGKLVTQALVLKSGTRIVMGKNHVFRFNHPEQARLERERSSAAIE--NPSEPVDWNFAQKE 631

  Fly   575 IMQNELSNDPIQTAIARLERQHE-EDKQVALEKQRQEYERQFQQLRNILSPSTPYAPYAPYDPLR 638
            :::.       |....:||.:.. :|.:...:|:::|.:...:|.|          .||..|
 Frog   632 LLEK-------QGIDIKLEMEKRLQDLEYQYKKEKEEADLTLEQQR----------LYADSD--- 676

  Fly   639 MGKITPNTPTSQMRVEKWAQERDEMFRRSLGQLKTDIM--RANSLVQEANFLAEEMEKKTKFSVT 701
                :.:....:...|.|         |.:..|:..:.  |..|:|:... |....:|:....|
 Frog   677 ----SGDDSDKRSCEESW---------RLISSLREKVPAGRVQSIVRRCG-LPSSGKKREPIRV- 726

  Fly   702 LQIPPANLSPNRRRGAFVSEPAIL---------VKR----------TNSGSQIWTMEKLENKLID 747
            .|||     ..||.|   .:|..|         ||.          .:|..:|..|     .:|.
 Frog   727 YQIP-----QRRRLG---KDPRWLTLADLKMQAVKEICYEVALNDFKHSRQEIEAM-----SVIK 778

  Fly   748 MREMYQEHKERVLNGLDEDNAKPQDPF------YESQENHNLIGVANIFLEV-----LFHDVKLD 801
            |:|:.:.:.:|.:|..:...|..:|.:      .|.....::.||.::...:     :..:|||.
 Frog   779 MKELCRTYGKRDINEKELWKAVARDVWDTVGVGEEDAGTKSVSGVQDLKAHIDKLTDILQEVKLQ 843

  Fly   802 YHTPIISQQGEVAGRLQ---VEIERIAGQMP-------QDRMCE-----------SVSESSGDSR 845
            .     :.:.|....|:   :::||:   ||       :|.:.|           .:.|.||...
 Frog   844 N-----NMKDEEIRSLRDRMIKMERV---MPLAQDNGDEDYLDEQSLPWYSNENQEIPEPSGSGL 900

  Fly   846 DEYDDPVDPTSNQI 859
            .....|.:|..:|:
 Frog   901 SPDHSPKEPRVDQL 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc-73	NP_001261000.1	KISc_KIF1A_KIF1B	4..359	CDD:276816	222/361 (61%)
		Kinesin_assoc	356..468	CDD:465047	52/170 (31%)
		FHA_KIF13	446..547	CDD:438758	41/106 (39%)
		KIF1B	741..786	CDD:463574	8/50 (16%)
		DUF3694	989..1243	CDD:463599
		CAP_GLY	1785..1850	CDD:460154
kif1c	XP_031755447.1	KISc_KIF1A_KIF1B	4..355	CDD:276816	222/361 (61%)
		Kinesin_assoc	352..524	CDD:465047	53/177 (30%)
		FHA_KIF1C	500..601	CDD:438780	40/105 (38%)