Protein Alignment Pgant1 and Galnt12

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001413928.1
• Gene: Galnt12 / 313233
• RGDID: 1562001
• Length: 576
• Species: Rattus norvegicus
• Alignment Length: 578
• Identity: 220/578 - (38%)
• Similarity: 309/578 - (53%)
• Gaps: 51/578 - (8%)

  Fly    42 LVRAAALRGHG-----RERFEAYSDSENEIARPATQSPYEQIIQLDLQKQKVGLGEQGVAVHLSG 101
            |:...||.|.|     |.|.............|....|.  :.:..|....:|...:.|.:.|.|
  Rat    21 LLALLALAGLGAVLRARSRSGTVDPVPTRTPHPGRHEPV--LPRPPLPADALGAKGEAVRLQLQG 83

  Fly   102 AAKERGDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPYSVLL 166
            ......:|..::..:|..||::::.:|.:.:..||||.:.::|.|:||..||||.|:||.:|.||
  Rat    84 EELRLQEESVQRHQINIYLSDRISLHRRLPERWNPLCREVKYDYDNLPKTSVVIAFYNEAWSTLL 148

  Fly   167 RTVHSTLSTCNEKALKEIILVDDGSDNVELGAKLDYYVRTRIPSGKVTILRLKNRLGLIRARLAG 231
            |||:|.|.|..:..|:|:|||||.||...|...|...: :::|  ||.::|...|.||:||||.|
  Rat   149 RTVYSVLETSPDILLEEVILVDDYSDREHLKEPLANEL-SQLP--KVRLIRASKREGLVRARLLG 210

  Fly   232 ARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKSFQVGGF 296
            |..|.|:||.|||.|||.:.||.|||||||.|..::|:.|:|||||.|.|:|..|..:. |:|||
  Rat   211 ASAARGEVLTFLDCHCECHEGWLEPLLQRIHEKESAVVCPVIDVIDWNTFEYLGNSGEP-QIGGF 274

  Fly   297 QWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQMDGWGGE 361
            .|...|.|..:|:||::..|......|      ||||||||||:.:|||..:||||..|:.||||
  Rat   275 DWRLVFTWHVVPQRERKLMRSPIDVIR------SPTMAGGLFAVSKRYFEYLGSYDTGMEVWGGE 333

  Fly   362 NLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGINTARMALVWMDEYINIFFLNR 426
            |||.||||||||||:||.|||.|||:|    |.:.|..|.....|:.|.|.||||::..:::...
  Rat   334 NLEFSFRIWQCGGTLETHPCSHVGHVF----PKQAPYSRSKALANSVRAAEVWMDDFKELYYHRN 394

  Fly   427 PDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVPTKDVQGWGKVHAVNSNI---CLD- 487
            |..:.. ..||||.|..||.||:||.|:|:|..:|||..||......:|.:.  |..:   |||
  Rat   395 PQARLE-PFGDVTERKKLRAKLQCKDFKWFLDTVYPELHVPEDRPGFFGMLE--NRGLRGYCLDY 456

  Fly   488 -DLLQNNEKPYNAGLYPCGKVLQKSQLFSFTNTNVLRNEL----SCATVQHSESPPYRVVMVPCM 547
             ...:||.:.:...||.|..:.| :|.|.:|:...:|...    :|..|:..:..   ::|..|.
  Rat   457 NPPSENNVEGHQVLLYLCHGMGQ-NQFFEYTSRQEIRYNTRQPEACIAVEEGKDV---LIMDLCK 517

  Fly   548 ----ENDEFNEQWRYEHQHIIHSNTGMCLDHQGLKSLDDAQVAP----CDPHSESQRW 597
                ||.||..|   |...::|..:|.|:  :..:...|...||    |. .|::|||
  Rat   518 DTVPENQEFVLQ---EDGTLVHKQSGKCV--EATEKEFDTSFAPHLRDCS-SSDNQRW 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	152/308 (49%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	36/147 (24%)
Galnt12	NP_001413928.1	None