Protein Alignment Pgant1 and Pgant35A

DIOPT Version :10

• Sequence 1: NP_611043.1
• Gene: Pgant1 / 36717
• FlyBaseID: FBgn0034025
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_313714.6
• Gene: Pgant35A / 1274571
• VectorBaseID: AGAMI1_002567
• Length: 663
• Species: Anopheles gambiae
• Alignment Length: 637
• Identity: 223/637 - (35%)
• Similarity: 326/637 - (51%)
• Gaps: 91/637 - (14%)

  Fly     6 RSF-YGKLIIFILVALCFILY---SKVQQNG---SPEEPPVAPLVRAAA-------------LRG 50
            ||| :|.:...:..::...||   |....||   |.:....||....||             |.|
Mosquito    19 RSFLWGVMAASLTWSISIYLYWNLSNTPTNGAGSSEQRLAKAPTSATAAEDTRQLILRNQNSLIG 83

  Fly    51 HGRERFEAYSDSENEIARPATQSPYEQIIQLDLQKQKV----------------GLGEQGVAVHL 99
            ...||....:....|..:...:..|.:.:. :.:|:::                |..|.|:..:
Mosquito    84 ASDERLHKKASKWAEKGKSLFKEKYARFMH-EKEKRRISHRLIDELQPMLIQPNGTDEFGMVQN- 146

  Fly   100 SGAAKER--GDEIYKKIALNEELSEQLTYNRSVGDHRNPLCAKQRFDSDSLPTASVVIIFFNEPY 162
               ::|:  .|..|:|.|.|..:|.:|...|.:.|.|:.||..|.:|. .||.||||:.|:||..
Mosquito   147 ---SEEQFIRDIGYRKHAFNVLVSNKLGPFRPIPDTRHKLCQAQVYDK-VLPVASVVMCFYNEHL 207

  Fly   163 SVLLRTVHSTLSTCNEKALKEIILVDDGSD--NVELGAKLDYYVRTRIPSGKVTILRLKNRLGLI 225
            ..|:|::|:.|.......|||:|||||.||  ::.:|.:|:..: .::.:.||.:||..:|.||:
Mosquito   208 ETLVRSIHTVLKRTPAYLLKELILVDDCSDFEDLTVGGQLEKEL-AQLGTNKVRLLRNTDREGLM 271

  Fly   226 RARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPIIDVIDANDFQYSTNGYKS 290
            |:|:.|||.|||.||||||:|.|.|:.|.||||.|||..||.:.:|:||:|:::.|.|:.:   .
Mosquito   272 RSRVYGARNATGQVLIFLDSHIEVNVDWIEPLLARIKHDRTILAMPVIDIINSDTFVYTAS---P 333

  Fly   291 FQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLFAIDRRYFWEVGSYDEQM 355
            ...|||.|..||.|.|||:...:|      ....:.|..|||||||||||||.||.|:|.||..|
Mosquito   334 LVRGGFNWGLHFKWDNLPKGSLER------DTDFVGPFNSPTMAGGLFAIDRAYFKELGEYDMGM 392

  Fly   356 DGWGGENLEMSFRIWQCGGTIETIPCSRVGHIFRDFHPYKFPNDRDTHGINTARMALVWMDEYIN 420
            |.|||||||:|||.|||||:||.:||||:||:||...||..|:.:||...|:.|:|.||||:||.
Mosquito   393 DVWGGENLEISFRAWQCGGSIELLPCSRIGHVFRKRRPYGSPDGQDTMIRNSLRLAHVWMDDYIR 457

  Fly   421 IFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLKNIYPEKFVP-------TKDV-----QG 473
            .|:..:|. ..|...|:|:.|..||::|.||.|.|||.||||:..||       .:|.     :.
Mosquito   458 YFYEQQPQ-AHHVPYGNVSERQRLRERLGCKPFRWYLDNIYPQLRVPGEKTSSDARDATQPKFEP 521

  Fly   474 WG----------KVHAVNSNICLDDLLQNNEKPYNAG----LYPCGKVLQKSQLFSFT-NTNVLR 523
            |.          ::...||::||...|.:.:..:..|    |.||.:|  |.|.:..| .:.::.
Mosquito   522 WHSRKRNYVASFQIRLSNSSLCLSTELDSEKSLWKKGSGLVLQPCLRV--KHQTWYETEKSELVL 584

  Fly   524 NELSCATVQHSESPPYRVVMVPCMENDEFNEQWRYEHQH---IIHSNTGMCL 572
            .:|.|.... |.:...|..:..|.|... ::.|::....   |.:..:|.||
Mosquito   585 GQLLCLDAP-SSATKGRPKLNKCHEMGG-DQAWKHRKTSGTPIYNIASGSCL 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant1	NP_611043.1	pp-GalNAc-T	152..461	CDD:133004	150/310 (48%)
		beta-trefoil_Ricin_Pgant1-like	468..601	CDD:467337	26/128 (20%)
Pgant35A	XP_313714.6	None