Protein Alignment Arf6 and ARL6

DIOPT Version :10

• Sequence 1: NP_523751.2
• Gene: Arf6 / 36699
• FlyBaseID: FBgn0013750
• Length: 175
• Species: Drosophila melanogaster
• Sequence 2: NP_001310442.1
• Gene: ARL6 / 84100
• HGNCID: 13210
• Length: 193
• Species: Homo sapiens
• Alignment Length: 177
• Identity: 77/177 - (43%)
• Similarity: 109/177 - (61%)
• Gaps: 8/177 - (4%)

  Fly     1 MGKL--LSKIFG--NKEMRILMLGLDAAGKTTILYKLK--LGQSVTTIPTVGFNVETVTYKNVKF 59
            ||.|  ||.:.|  .||:.:|.||||.:|||||:.|||  ..||...:||:||::|.....::.|
Human     1 MGLLDRLSVLLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQSQNILPTIGFSIEKFKSSSLSF 65

  Fly    60 NVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARTELHRIIN--DREMRDAIILIFAN 122
            .|:|:.||.:.|.||.|||...|.:|||:|.:||.|:..|:.||..::|  |.:.|...||.|||
Human    66 TVFDMSGQGRYRNLWEHYYKEGQAIIFVIDSSDRLRMVVAKEELDTLLNHPDIKHRRIPILFFAN 130

  Fly   123 KQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLSEGLIWL 169
            |.||.||:...::.:.|.|..|:|:.|::..|.|..|:||.||:.||
Human   131 KMDLRDAVTSVKVSQLLCLENIKDKPWHICASDAIKGEGLQEGVDWL 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arf6	NP_523751.2	P-loop containing Nucleoside Triphosphate Hydrolases	1..174	CDD:476819	77/177 (44%)
ARL6	NP_001310442.1	Arl6	19..180	CDD:206722	69/159 (43%)