Protein Alignment CG8079 and SQS1

DIOPT Version :10

• Sequence 1: NP_611023.1
• Gene: CG8079 / 36689
• FlyBaseID: FBgn0034002
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_014175.1
• Gene: SQS1 / 855497
• SGDID: S000005168
• Length: 767
• Species: Saccharomyces cerevisiae
• Alignment Length: 807
• Identity: 137/807 - (16%)
• Similarity: 233/807 - (28%)
• Gaps: 336/807 - (41%)

  Fly     2 SLPAEEEDLADTVAKYDS----IELKSIQDL---ETCEQQQLLQYVEKLHGII--RKYDTKL--- 54
            |:|..|.||.|..|.::.    |..|:|:|.   ...:.:.:     |:.|:.  .:||:..
Yeast    51 SIPLGEGDLDDVGADFNPGRAFISPKTIEDYYFGRDAKSRSM-----KMGGLRPGNRYDSSTDLQ 110

  Fly    55 ---ASYKQKLLHYVSREE--------------KVSCDKASQATESE----------LQECQYSME 92
               |:::::.:.:|..:|              |.....:.:..|.|          ..:.:|...
Yeast   111 AGRAAFRKRPMQFVKAKEVYDPSHNMIQKLRAKNETKNSEEIVEREADVFEEPGKMTSDVEYINN 175

  Fly    93 NDEDTNKKDQPNDLSATDAFS------------FVDEMRQAAKHAENLNNFVYEH---------- 135
            .|.:....|..|..|...:.|            ||||..|.:.....:.....|.
Yeast   176 EDSENEDDDSQNSPSTDHSLSSNESKVEDGDLFFVDEEAQQSPDLTKIKRVCIEEIARPREVAIE 240

  Fly   136 -----TSGMY------------------------YDPKTGYYYNAEYGLYYDGNNGCYYSYD--- 168
                 |.|..                        |.|..||..|..:|::...::.....|:
Yeast   241 FDPILTIGKVELSVSEGNESKEISVDVPNKGNKTYHPFAGYISNVLHGMHTSDSDNDELDYEIET 305

  Fly   169 --HAKDSYEFHSQAQV------------------------------------------QANDAAK 189
              :::..||..:.::|                                          :.|:...
Yeast   306 ENNSEPLYESSASSEVDQGFNYVGQRHNSRADNNLLPSPSPQLTEDIKCLSINGTKTFEGNNDNL 370

  Fly   190 PESEDEDLEVQFDE----------------LGGV------------------------ITD---- 210
            |....|:||..|.|                :|||                        :||
Yeast   371 PSPASEELEFGFKEEDFVINTNDIVVSNIRMGGVDNSYYLRCYRLLGDYDFHWIDQDLLTDFVVD 435

  Fly   211 -----------------HETLKKIKAEK--------QKAKDQAEKSKRKAKKKK----------- 239
                             :..:.||:..:        ..:.|:.:..:..:.:..
Yeast   436 ELGLPEDRLPAYLNFIKNSLIPKIEPAEPTYSDIPISDSSDEGDSYEGDSYEDDEDMASSVVHSD 500

  Fly   240 -----------SKKHSKKRSKK------ERRHKSKKRHRHSDDERSNDAEEGELSQSSDSSSDSS 287
                       :.||..:|.|.      |.:.|.||:....||..:.|.|..|..||..|....:
Yeast   501 IEEGLDDLIAYTLKHDTERFKTFETKSLETKGKGKKKKLLIDDALALDTETLETLQSKFSKRIET 565

  Fly   288 NEDSSSNTEDSSVPVFKAAGRFQDIAKKYPPSLRIIVQETNVESLKVGSLHLITYKGGSLGREGA 352
            ........||.   :.:......|:.||||..|.|
Yeast   566 KAKKRKAKEDF---IDQENRNSNDMLKKYPYGLHI------------------------------ 597

  Fly   353 HDVIIPDVNVSKCHLKFKYENKLGIYQCLDLGSRNGTILNGSPMSSDAMDLVHGSVITLGQTRLL 417
                        .::|.::|:.|         |||...|...|:..      ||:...:   ::.
Yeast   598 ------------QNIKDEFESFL---------SRNNDRLTFPPLDP------HGNKTVM---KIA 632

  Fly   418 CHVHEGNSTCGLCEPGLLIENSPPVVAAVASSTASVLSHKEQLKKLQRKYGLENEKFVDTSGNGQ 482
            .|.:..:|..|                 .|:.|:.|:   |::||  .|:...|...:|.....:
Yeast   633 KHYNMKSSKIG-----------------KANHTSVVV---EKIKK--TKWSSPNYSLIDQLMRQR 675

  Fly   483 SNY---------NDRAATRRVQV--GSSTDKEKTEVACVNTEIGSSNKGFKMLSKLGWQKGEKLG 536
            ..:         .::||..|.:.  |....||...|.....|||:.|.|.:||.||||:.||.||
Yeast   676 PVFMRIDIRRPREEQAAFERTKTIRGKFHVKEGEIVGQNAPEIGNENIGRRMLEKLGWKSGEGLG 740

  Fly   537 KTNASAGLLEPINVVANEGTSGLGNSD 563
             ...:.|:.|||.....:..|||.:|:
Yeast   741 -IQGNKGISEPIFAKIKKNRSGLRHSE 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8079	NP_611023.1	OCRE_VG5Q	124..177	CDD:293883	12/96 (13%)
		OCRE repeat 1	129..136	CDD:293883	1/21 (5%)
		OCRE repeat 2	137..144	CDD:293883	2/30 (7%)
		OCRE repeat 3	145..152	CDD:293883	3/6 (50%)
		OCRE repeat 4	153..159	CDD:293883	1/5 (20%)
		OCRE repeat 5	162..169	CDD:293883	1/11 (9%)
		FHA_AGGF1	316..433	CDD:438738	17/116 (15%)
		G-patch	516..560	CDD:396249	18/43 (42%)
SQS1	NP_014175.1	R3H_G-patch	597..654	CDD:100075	17/136 (13%)
		G-patch	721..764	CDD:396249	19/43 (44%)