Protein Alignment CG8079 and Rbm5

DIOPT Version :10

• Sequence 1: NP_611023.1
• Gene: CG8079 / 36689
• FlyBaseID: FBgn0034002
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001094018.1
• Gene: Rbm5 / 300996
• RGDID: 1305059
• Length: 815
• Species: Rattus norvegicus
• Alignment Length: 602
• Identity: 120/602 - (19%)
• Similarity: 190/602 - (31%)
• Gaps: 216/602 - (35%)

  Fly    52 TKLASYKQKLLHYVSR-----EEKVSCDKASQATESELQECQYSMENDEDTN-------KKDQPN 104
            |:...|.|....:..:     |...|....:..|.:.......|.:....|:       ::.||:
  Rat   369 TQYTQYSQDYQQFYQQQTGGLESDASATSGTTVTTTSAAVVSQSPQLYNQTSNPPGSPTEEAQPS 433

  Fly   105 DLSATDAFSFVDEMRQAA---------KHA-ENLNNFVYEHTSGMYYDPKTGYYYNAEYGLYYDG 159
            ..::|.|        .||         |:| .:.:.:.|:.:||.||||.||.||:.....||:.
  Rat   434 TSTSTQA--------PAASPTGVVPGTKYAVPDTSTYQYDESSGYYYDPTTGLYYDPNSQYYYNS 490

  Fly   160 NNGCYYSYDHAKDSYEFHSQAQVQANDAAKPESEDEDLEVQFDELGGVITDHETLKKIKAEKQKA 224
            ....|..:|..|::|.  ..|:..:|..|...|..|..|            .:...|.|..:|.|
  Rat   491 LTQQYLYWDGEKETYV--PAAESSSNQQAGLPSTKEGKE------------KKEKPKSKTAQQIA 541

  Fly   225 KDQAEKSKRKAKKKKSKKHS--------------------------KKRSKKERRHKSKKRHRHS 263
            ||....:|...|:|::.|:|                          ||.:..||:....:..|:.
  Rat   542 KDMERWAKSLNKQKENFKNSFQPVNSLREEERRESAAADAGFALFEKKGALAERQQLIPELVRNG 606

  Fly   264 DDERSNDAEEGELSQSSDSSSDSSNEDSSSNTEDSSVPVFKAAGRFQDIAKKYPPSLRIIVQETN 328
            |:|  |..:.|.::.   .|.||.||                                    |..
  Rat   607 DEE--NPLKRGLVAA---YSGDSDNE------------------------------------EEL 630

  Fly   329 VESLKVGSLHLITYKGGSLGREGAHDVIIPDVNVSKCHLKFKYENKLGIYQCL-DLGSRNGTILN 392
            ||.|:.....|..:|               .:....|..:|...:.|..:|.| ||..:|..|..
  Rat   631 VERLESEEEKLADWK---------------KMACLLCRRQFPNRDALVRHQQLSDLHKQNMDIYR 680

  Fly   393 GSPMSSDAMDLVHGSVITLGQTRLLCHVHEGNSTCGLCEPGLLIENSPPVVAAVASSTASVLSHK 457
            .|.:|...::.:
  Rat   681 RSRLSEQELEAL----------------------------------------------------- 692

  Fly   458 EQLKKLQRKYGLENEKFVDTSGNGQSNYNDRAATRRVQVG-----SSTDKEKTEVACVNTE---- 513
             :|::.:.|                  |.||||.||.:.|     ....|::.:...||.|
  Rat   693 -ELREREMK------------------YRDRAAERREKYGIPEPPEPKRKKQFDAGTVNYEQPTK 738

  Fly   514 --IGSSNKGFKMLSKLGWQKGEKLGKTNASAGLLEPINVVANEGTSGLGNSDPVLSSSRTIDKRK 576
              |..||.|.|||..:||::|..||:  ...|:..||........:|||........|.. |..|
  Rat   739 DGIDHSNIGNKMLQAMGWREGSGLGR--KCQGITAPIEAQVRLKGAGLGAKGSAYGLSGA-DSYK 800

  Fly   577 LANLKITQARYQRASDM 593
            .|   :.:|.:.|.::|
  Rat   801 DA---VRKAMFARFTEM 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8079	NP_611023.1	OCRE_VG5Q	124..177	CDD:293883	18/53 (34%)
		OCRE repeat 1	129..136	CDD:293883	1/6 (17%)
		OCRE repeat 2	137..144	CDD:293883	5/6 (83%)
		OCRE repeat 3	145..152	CDD:293883	4/6 (67%)
		OCRE repeat 4	153..159	CDD:293883	2/5 (40%)
		OCRE repeat 5	162..169	CDD:293883	1/6 (17%)
		FHA_AGGF1	316..433	CDD:438738	17/117 (15%)
		G-patch	516..560	CDD:396249	15/43 (35%)
Rbm5	NP_001094018.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..93
		RRM1_RBM5	93..179	CDD:410146
		zf-RanBP	181..210	CDD:395516
		RanBP2-type Zn finger	185..204	CDD:275375
		RRM2_RBM5	229..314	CDD:410149
		Required for interaction with U2AF2. /evidence=ECO:0000250	321..809		118/595 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	407..468		11/68 (16%)
		Sufficient for interaction with ACIN1, PRPF8, SFRS3, SNRPB, SNRPN, SNRNP70 and SNRNP200. /evidence=ECO:0000250	452..535		26/96 (27%)
		OCRE_RBM5	455..510	CDD:293887	18/56 (32%)
		OCRE repeat 1	460..467	CDD:293887	1/6 (17%)
		OCRE repeat 2	468..475	CDD:293887	5/6 (83%)
		OCRE repeat 3	476..483	CDD:293887	4/6 (67%)
		OCRE repeat 4	484..491	CDD:293887	2/6 (33%)
		OCRE repeat 5	493..500	CDD:293887	1/6 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	508..540		8/43 (19%)
		G-patch	743..787	CDD:396249	17/45 (38%)