Protein Alignment GPHR and YHR078W

DIOPT Version :10

• Sequence 1: NP_611016.2
• Gene: GPHR / 36682
• FlyBaseID: FBgn0033995
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_011945.1
• Gene: YHR078W / 856477
• SGDID: S000001120
• Length: 552
• Species: Saccharomyces cerevisiae
• Alignment Length: 546
• Identity: 121/546 - (22%)
• Similarity: 207/546 - (37%)
• Gaps: 177/546 - (32%)

  Fly    24 FFNK-----ELFKHYEIRHISVQLIFSSTFALSITMFELIIFEI----IDVLESSSRYFHWRLGL 79
            |.||     .|..|..::  |::::||..........|:|:::|    :|...:....:.|.|..
Yeast    65 FINKFYTEYSLPSHKVLQ--SLRVLFSLAMMTYTVTIEIILWQIKVAGMDKEVTFITTWVWPLTA 127

  Fly    80 TLLLFMTTAVIPIYICYSVIHSISFFSDKW--VRILTTFCWFIFIYGLWRIGDPFPLLS-ASHGI 141
            .:|.|:.....|.:|..|:::  .|::||:  .|::...|  |.:..|      ..||| .:.|.
Yeast   128 IMLSFILILFQPFFIIISLLN--KFYNDKFDIDRLIIVTC--IILSTL------IALLSYINIGP 182

  Fly   142 FTIEQGV-SRISVIGVTVMAILSGFGAVNYPY------------TSMSYFIKPVSRNDIICFERR 193
            |...:.: :|:|:.||||||.|||...|:..|            |.||   .|..||
Yeast   183 FQYTKNILTRLSIGGVTVMASLSGLATVSSLYYNFLVIWHKFRNTPMS---DPSFRN-------- 236

  Fly   194 LALTVEMLSAKKRKIAMAIYNHNKLNPSKPRIWDMLASAVQRNTNSGEDINQLKQEVYGLEELL- 257
                              |.|.|  |.||..:|...|...::..:...:|.|..|.:..|||.:
Yeast   237 ------------------INNSN--NNSKSLLWTTDAYIEEKIQDYEHNIEQNVQILRSLEEEVG 281

  Fly   258 -RSVF------------LELSSLKNMEERQRWSQTLKGKYFNVLGHFFSVYCVYKIFMCCINII- 308
             .|.|            |||..|:.:.::....:|.| |.|.|   .|.:||::|:.:..:..|
Yeast   282 ENSTFKAELMEKIAWYQLELGKLEALLQQSPQVRTFK-KAFEV---GFIIYCLHKLIITFLKRIP 342

  Fly   309 -----------------FDRVGRKDPVTRGLEIAIHWCGFNI-DFAFWN---QH----------- 341
                             |......||:  .:.||      || ||:|:.   ||
Yeast   343 YIIYHSLKYPDDYDYENFSENAASDPL--AITIA------NILDFSFFRFNYQHDLDSLTKQISL 399

  Fly   342 ---ISFLLVGCIVITSIRGLLLTL--TKF----FYRISSSKSSNIIV------------------ 379
               ||..|.....:.:....::||  .||    .:.:.:..::|::.
Yeast   400 FLSISLFLCCLSAVNTTISYVVTLLPIKFQILALFAMQNDDTANVLPEYTNNSSYKGKKRNYSQE 464

  Fly   380 ---------LILGQIMGMYFCSSVLLMRMNMPAEYRVIITEVLG------NLHFNFYHRWFDVIF 429
                     |::.::.|:|..::.|::|.::|.|....:.|:||      |:..:   .|||.::
Yeast   465 QKGISLIKNLVVSELTGVYVLATTLMVRSHLPFEVSQRLKELLGGKFTVPNIVID---SWFDEVY 526

  Fly   430 LVSALTTIIVL-----YLSRKPVRVD 450
            ..:.:.|.|.:     .||.|.|.|:
Yeast   527 AFACVFTFICIRIAERKLSTKKVSVE 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPHR	NP_611016.2	GPHR_N	141..208	CDD:463623	20/79 (25%)
		ABA_GPCR	277..445	CDD:463577	48/247 (19%)
YHR078W	NP_011945.1	GPHR_N	183..262	CDD:463623	28/109 (26%)
		ABA_GPCR	309..542	CDD:463577	46/247 (19%)