DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GPHR and AgaP_AGAP011252

DIOPT Version :9

Sequence 1:	NP_611016.2	Gene:	GPHR / 36682	FlyBaseID:	FBgn0033995	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	XP_309392.4	Gene:	AgaP_AGAP011252 / 1270674	VectorBaseID:	AGAP011252	Length:	436	Species:	Anopheles gambiae

Alignment Length:	438	Identity:	315/438 - (71%)
Similarity:	367/438 - (83%)	Gaps:	3/438 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 MIFFAGGWLFFNKELFKHYEIRHISVQLIFSSTFALSITMFELIIFEIIDVLESSSRYFHWRLGL 79
            :|||.|||:||.|:||::|||||:.||||||||.|||:|||||||||||..|:||||||||||||
Mosquito     1 LIFFIGGWVFFVKQLFRNYEIRHVFVQLIFSSTLALSLTMFELIIFEIIGFLDSSSRYFHWRLGL 65

  Fly    80 TLLLFMTTAVIPIYICYSVIHSISFFSDKWVRILTTFCWFIFIYGLWRIGDPFPLLSASHGIFTI 144
            ||||.|..||||..|.||.|.::.....|||:.|||..|..::||.|||||||||||.|.|||||
Mosquito    66 TLLLIMVIAVIPYLIAYSCISNVRIVPAKWVQPLTTLIWLCYLYGFWRIGDPFPLLSVSRGIFTI 130

  Fly   145 EQGVSRISVIGVTVMAILSGFGAVNYPYTSMSYFIKPVSRNDIICFERRLALTVEMLSAKKRKIA 209
            ||.||||.|:|||||||||||||||||||||||||:|||::|::..||||..|::|:..||::||
Mosquito   131 EQAVSRIGVVGVTVMAILSGFGAVNYPYTSMSYFIRPVSQSDVVNLERRLLQTMDMILVKKKRIA 195

  Fly   210 MAIYNHNKLNPSKPRIWDMLASAVQRNTNSGEDINQLKQEVYGLEELLRSVFLELSSLKNMEERQ 274
            :. ...||.| .|..||.|::|..||...: |:|.||:.|:..||||.|.:|||..|:|||:||:
Mosquito   196 LD-RRRNKPN-QKQSIWGMISSVTQRPAGA-ENIGQLRLEISALEELSRQLFLEAHSMKNMQERE 257

  Fly   275 RWSQTLKGKYFNVLGHFFSVYCVYKIFMCCINIIFDRVGRKDPVTRGLEIAIHWCGFNIDFAFWN 339
            ||:.||:||||||||||||:||::|||:|.|||||||||:|||||||:|||:|||||::|.|||:
Mosquito   258 RWAATLQGKYFNVLGHFFSLYCLWKIFICTINIIFDRVGKKDPVTRGIEIAVHWCGFDMDIAFWS 322

  Fly   340 QHISFLLVGCIVITSIRGLLLTLTKFFYRISSSKSSNIIVLILGQIMGMYFCSSVLLMRMNMPAE 404
            ||:|||||||||:|||||||||||||||:||||||||||||:|.|||||||||||||||||||||
Mosquito   323 QHVSFLLVGCIVVTSIRGLLLTLTKFFYKISSSKSSNIIVLVLAQIMGMYFCSSVLLMRMNMPAE 387

  Fly   405 YRVIITEVLGNLHFNFYHRWFDVIFLVSALTTIIVLYLSRKPVRVDDS 452
            ||||||||||.|||||||||||||||||||.||:||||..||..||.|
Mosquito   388 YRVIITEVLGGLHFNFYHRWFDVIFLVSALATIVVLYLLHKPPNVDTS 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GPHR	NP_611016.2	GPHR_N	141..208	CDD:289314	48/66 (73%)
GPHR	NP_611016.2	ABA_GPCR	277..443	CDD:289215	142/165 (86%)
AgaP_AGAP011252	XP_309392.4	GPHR_N	127..194	CDD:289314	48/66 (73%)
AgaP_AGAP011252	XP_309392.4	ABA_GPCR	260..425	CDD:289215	141/164 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	308	1.000	Domainoid score	I3532
eggNOG	1	0.900	-	-		E1_KOG2417
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9475
Inparanoid	1	1.050	659	1.000	Inparanoid score	I2065
OMA	1	1.010	-	-		QHG55010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003368
OrthoInspector	1	1.000	-	-		otm49614
Panther	1	1.100	-	-	LDO	PTHR15948
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2255
TreeFam	1	0.960	-	-
	12	11.930