Protein Alignment Cyp317a1 and ERG11

DIOPT Version :10

• Sequence 1: NP_611004.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 516
• Identity: 102/516 - (19%)
• Similarity: 179/516 - (34%)
• Gaps: 157/516 - (30%)

  Fly    34 DIPHERPKKLWPIIRQIMTQTLSTEAMK------AEHYSAIYKKFKGSGPFCGFYALLQPRALIL 92
            |.|:.|..:....::..:|:    ||.|      ||.   :||.|:.|
Yeast   141 DCPNSRLMEQKKFVKGALTK----EAFKSYVPLIAEE---VYKYFRDS----------------- 181

  Fly    93 DRELIRQIMIKDFWNFNDR--GLYCNQKSDPLSGDLYALRGESWKEMRQKLDPSLEGDRMSLLYD 155
                      |:| ..|:|  |......:.|......|.|....||||.|||..         :.
Yeast   182 ----------KNF-RLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTD---------FA 226

  Fly   156 CLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMRRYVLSSLAKCVFGLNAEQRKTYPLEDFEQMTEL 220
            .||.:.::....:|....:.|  ..|.:|  |.:...:::.....|..|:||...::|.:.:..|
Yeast   227 YLYSDLDKGFTPINFVFPNLP--LEHYRK--RDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSL 287

  Fly   221 ALNS-HKHGYLMNLMMIRFPNFCRMLRMRRTPKQAEEYFIKLLTSIVEQRETSGKPQKDYLQLLI 284
            ..|| :|.|..|.                                           .::...|||
Yeast   288 MKNSTYKDGVKMT-------------------------------------------DQEIANLLI 309

  Fly   285 DVKALEFITHQYEADKELGAHLQNELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREE 349
            .|                               |..|...:|.|.:::|..||..|::|..:.||
Yeast   310 GV-------------------------------LMGGQHTSAATSAWILLHLAERPDVQQELYEE 343

  Fly   350 VKKAIERHDGHITHEGIKSLSFMGQVINETLRMHPITPYILRRTLNDYAVPDHPKYILVKELFLI 414
            ..:.::.....:|::.::.:..:.|.|.||||||.....:.|:.:.|..|| :..|::.....::
Yeast   344 QMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVP-NTSYVIPAGYHVL 407

  Fly   415 IPTHAIHHDPDIYPDPEEFKPDRWSGPRDSL------QEQGTWFG------------FGVGARSC 461
            :.....|...:.:|:..:|...||:  :||.      :|....||            ||.|...|
Yeast   408 VSPGYTHLRDEYFPNAHQFNIHRWN--KDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRC 470

  Fly   462 IGIQFAQLQLRLALALLLSEYEFSLNTRKPLINLEDGIALTLMPLG----VIEPGNEERAV 518
            ||..||..||.:.:::.:...::.....| .:...|..::..:|.|    :.|..|.|:.:
Yeast   471 IGEHFAYCQLGVLMSIFIRTLKWHYPEGK-TVPPPDFTSMVTLPTGPAKIIWEKRNPEQKI 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_611004.1	CYP6-like	74..509	CDD:410679	87/459 (19%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	99/505 (20%)