Protein Alignment Cyp317a1 and Cyp3a73

DIOPT Version :10

• Sequence 1: NP_611004.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: XP_038945885.1
• Gene: Cyp3a73 / 498198
• RGDID: 1595705
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 550
• Identity: 129/550 - (23%)
• Similarity: 245/550 - (44%)
• Gaps: 97/550 - (17%)

  Fly     2 WIIFLIIGLLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEHYS 66
            |::..||       |||...........::...||..:|   .|.:..::           .:|.
  Rat    12 WLLLAII-------LVLFYRFGTRTHGIFKKQGIPGPKP---LPFLGTVL-----------NYYR 55

  Fly    67 AIYK----KFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKS-DP---LS 123
            .::|    .:|..|...|.:....|...|:|.|:|:.:::|:.::     ::.|::: .|   :|
  Rat    56 GLWKFDMECYKKCGKIWGLFDGQTPVFAIMDTEMIKSVLVKECFS-----VFTNRRNIGPVGIMS 115

  Fly   124 GDLYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMRR 188
            ..:...:.|.||..|..|.|:....|:..::..:....:.|:..:...:  :....:.::::...
  Rat   116 KSISVAKDEEWKRYRAFLSPTFTSGRLKEMFPIIEHYGDILVKYLKQKV--EKGKPLAMKEVFGA 178

  Fly   189 YVLSSLAKCVFGLN-----------AEQRKTYPLEDFEQMTELALNSHKHGYLMNLMMIRFP--- 239
            |.:..:....|.:|           .|:.|.:...||...             :.|.::.||
  Rat   179 YSMDVITSTSFEVNINSINNPKDPFVEKVKKFQRFDFFDP-------------LFLSVVLFPFLT 230

  Fly   240 NFCRMLRMRRTPKQAEEYFIKLLTSIVEQR-ETSGKPQKDYLQLLIDVKALEFITHQYEADKELG 303
            ....||.:...||.:..:|.|.:..:.:.| ::..|.:.|:|||:::       .|....||...
  Rat   231 PIYEMLNICLFPKDSVAFFQKFVYRMKQTRLDSKHKHRVDFLQLMMN-------AHNNSKDKVSH 288

  Fly   304 AHLQN-ELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGIK 367
            ..|.: |:.|.|::|:.|.||.|::|||:|||.||.||:.|.:::||:.:|:. :....|::.:.
  Rat   289 KALSDIEIVAQAIIFIFASYETTSSTLSFVLYSLATHPDSQKKLQEEIDRALP-NKAPPTYDTVM 352

  Fly   368 SLSFMGQVINETLRMHPITPYILRRT------LNDYAVPDHPKYILVKELFLIIPTHAIHHDPDI 426
            .:.::..|:|||.|::|| .|.|.|.      |:...:|        |...::||.:.:.|||..
  Rat   353 EMEYLDMVLNETPRLYPI-GYRLERVCKKDIKLDGVFIP--------KGSVVMIPFYTLQHDPQH 408

  Fly   427 YPDPEEFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEYEFSL----- 486
            :|:||||.|:|:|.......:...:..||.|.|:|||::||.:.::|||..:|..:.|.|
  Rat   409 WPEPEEFLPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQLCEETQ 473

  Fly   487 ----NTRKPLINLEDGIALTLMPLGVIEPG 512
                .:|:.|...|..|.|.::|...:..|
  Rat   474 IPLKLSRQRLFGPEKPIVLKVVPRDAVITG 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_611004.1	CYP6-like	74..509	CDD:410679	115/469 (25%)
Cyp3a73	XP_038945885.1	CYP3A	67..493	CDD:410743	113/462 (24%)