Protein Alignment Cyp317a1 and cyp-25A3

DIOPT Version :10

• Sequence 1: NP_611004.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_001040850.1
• Gene: cyp-25A3 / 4363046
• WormBaseID: WBGene00014697
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 508
• Identity: 125/508 - (24%)
• Similarity: 241/508 - (47%)
• Gaps: 70/508 - (13%)

  Fly     5 FLIIGLLVLGLL--VLLIIAARYQRDYWR-YLDIPHERPKKLWPIIRQIMTQTLSTEAMKA---- 62
            |||:..:::.|:  ::.:|.||.:|...| .:.:....|..|...::||:.:       ||
 Worm     3 FLILTSILVSLVSFIIYVILARKERFRLRGKIGLSGPEPHWLMGNLKQIIER-------KAKLGY 60

  Fly    63 ----EHYSAIYKKFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRG----LYCNQKS 119
                :.|:.::|:|   |...|.|...|....|.:.|.|:::.||:|.||:||.    :..|:..
 Worm    61 DDSYDWYNKLHKQF---GETFGIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIEDNKLK 122

  Fly   120 DPLSGDLYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQK 184
            :.|..:.|.   ..||..|..:.|.....:|..:::.::.:.:..|..:.....|.....::..
 Worm   123 ESLLQNTYE---SGWKHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEILKEKASSGQKWDIYDD- 183

  Fly   185 IMRRYVLSSLAKCVFGLNA----EQRKTYPLEDFEQMTELALNSHKHGYLMNLMMIRFPNFCRML 245
             .:...|..:.||.|.:::    ::...:.:...:.:|.:.:   :|..:::...: ||...::.
 Worm   184 -FQGLTLDVIGKCAFAIDSNCQRDRNDVFYVNARKFITNIDI---RHSKIISTSFL-FPELSKLW 243

  Fly   246 RM--RRTP-KQAEEYFIKLLTSIVEQRE-TSGKPQKDYLQLLIDVKALEFITHQYEADKELGAHL 306
            ::  |.|. .:||...::.|..:.|:|. ..|....|.|:||::          .|.||......
 Worm   244 KVLYRFTDLAKAEIPLVEGLADVYERRRGGEGSDSVDLLKLLLN----------REDDKSKPMTK 298

  Fly   307 QNELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGIKSLSF 371
            | |:..:...||.||||.|:..::|..|.|:.:|.:|.::.||:.:|  :.:|.:|::.|.::.:
 Worm   299 Q-EVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEA--KENGGLTYDSIHNMKY 360

  Fly   372 MGQVINETLRMH-PITPYILRRTLNDYAVPD--HPKYILVKELFLIIPTHAIHHDPDIYPDPEEF 433
            :..|..||||.: |:..:..||.|.|..:..  :||..:|    :.:| |.:|.:|:.:..||||
 Worm   361 LDYVYKETLRCYPPVIHFSNRRCLKDITIRGQFYPKGAIV----VCLP-HTVHRNPENWDSPEEF 420

  Fly   434 KPDR---WSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEYE 483
            .|:|   |.....||:    |..||||.|.|:|::||:::.:..:|.||..:|
 Worm   421 HPERFENWEEKSSSLK----WIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFE 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_611004.1	CYP6-like	74..509	CDD:410679	107/428 (25%)
cyp-25A3	NP_001040850.1	CYP3A-like	73..495	CDD:410678	108/431 (25%)