Protein Alignment Cyp317a1 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_611004.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 140/543 - (25%)
• Similarity: 246/543 - (45%)
• Gaps: 78/543 - (14%)

  Fly    12 VLGLL---------------VLLIIAARYQRDYW---RYLDIPHERPKKLWPIIRQIMTQTLSTE 58
            |||||               |||.:...|....:   |.|.|.|..|.   |.:..:|   ...:
  Rat     3 VLGLLKFEVSGTVVTVTLSVVLLALLKWYSTSAFSRLRKLGIRHPEPS---PFVGNLM---FFRQ 61

  Fly    59 AMKAEHYSAIYKKFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDR---GLYCNQKSD 120
            .....|.. :.:::   ||.||:|...:...:|.|.::|:::::::|.||::|   ||      :
  Rat    62 GFWESHLE-LRERY---GPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNRMASGL------E 116

  Fly   121 P--LSGDLYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQ 183
            |  ::..:..||...|:|:|..|..:...::::.:...:.:..|.||..:..:..|  .....||
  Rat   117 PKLIADSVLMLRDRRWEEVRGALMSAFSPEKLNEMTPLISQACELLLSHLKHSAAS--GDAFDIQ 179

  Fly   184 KIMRRYVLSSLAKCVFGLNAEQRKTYPLEDFEQMTELALNSHKHGYLMNLMMIRFPNFCRMLRMR 248
            :....:..:.:|...||:....:.. |.:.|.|..:..........|:.| ::.||:....|...
  Rat   180 RCYCCFTTNVVASVAFGIEVNSQDA-PEDPFVQHCQRVFAFSTPRPLLAL-ILSFPSIMVPLARI 242

  Fly   249 RTPKQAEE---YFIKLLTSIV--EQRETSGKPQKDYLQLLID---------VKALEFITHQYEAD 299
            ...|..:|   :|..|:.:::  ..::|:.:.:.|:||:::|         |:|.:.:|....:.
  Rat   243 LPNKNRDELNGFFNTLIRNVIALRDKQTAEERRGDFLQMVLDAQRSMSSVGVEAFDMVTEALSSA 307

  Fly   300 KELGAHLQ-------------NELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVK 351
            :.:|...|             :|:|..|.:||.||:|.|.||||::.|.||.|||.|.|:.:||.
  Rat   308 ECMGDPPQRCHPTSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLLKEVD 372

  Fly   352 KAIERHDGHITHEGIKSLSFMGQVINETLRMHPITPYILRRTLNDYAV-PDHPKYILVKELFLII 415
            ..:|:|.........:.|.::..|:.|||||:|......|....|..| ..|    :.....|.|
  Rat   373 LFMEKHPAPEYCNLQEGLPYLDMVVAETLRMYPPAFRFTREAAQDCEVLGQH----IPAGSVLEI 433

  Fly   416 PTHAIHHDPDIYPDPEEFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLS 480
            ...|:||||:.:|:||.|.|:|::......|:..|:..||.|.|||:|::...|.::|.|..:|.
  Rat   434 AVGALHHDPEHWPNPETFDPERFTAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLH 498

  Fly   481 EYEFSL--NTRKPLINLEDGIAL 501
            ::.|..  .|:.|| .||...||
  Rat   499 KFRFEACPETQVPL-QLESKSAL 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_611004.1	CYP6-like	74..509	CDD:410679	123/463 (27%)
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	123/465 (26%)