Protein Alignment Cyp317a1 and cyp-13A7

DIOPT Version :10

• Sequence 1: NP_611004.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_496114.1
• Gene: cyp-13A7 / 188362
• WormBaseID: WBGene00000372
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 138/544 - (25%)
• Similarity: 240/544 - (44%)
• Gaps: 82/544 - (15%)

  Fly    10 LLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEHYSAIYKKFKG 74
            |:.:.:.|.:|....:...:|....:...|......:|.: .|...:..|:|   :|...||:
 Worm     6 LIAIAIFVGIISYYLWIWSFWIRKGVKGPRGLPFLGVIHK-FTNYENPGALK---FSEWTKKY-- 64

  Fly    75 SGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSDPLSG---DLYALRGESWKE 136
             ||..|....::...:|.|.|.:.::.:|.|.||..|.|...| .||...   .|.|.:|..||.
 Worm    65 -GPVYGITEGVEKTLVISDPEFVHEVFVKQFDNFYGRKLTAIQ-GDPNKNKRVPLVAAQGHRWKR 127

  Fly   137 MRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMRRYVLSSLAKCVFGL 201
            :|....|:.....:..:...:.|...:|:.::...  |....|:.:.:..:.:.:..:.|...|
 Worm   128 LRTLASPTFSNKSLRKIMGTVEESVTELVRSLEKA--SAEGKTLDMLEYYQEFTMDIIGKMAMG- 189

  Fly   202 NAEQRKTYPLEDFEQMTELALNSHKHGYLMNLMMI----------------RFPNFCRMLRMRRT 250
               |.|:....:  .|.:......|.| ..|:.||                :||:    |:|...
 Worm   190 ---QEKSLMFRN--PMLDKVKTIFKEG-RNNVFMISGIFPFVGIALRNIFAKFPS----LQMATD 244

  Fly   251 PKQAEEYFIKLLTSIVEQRET--------SGKPQKDYLQLLIDVKA-LEFITHQYEAD------K 300
            .:...|   |.|...:||||.        ||:|| |::.|.:|.:: ::|...:.|.|      .
 Worm   245 IQSILE---KALNKRLEQREADEKAGIEPSGEPQ-DFIDLFLDARSTVDFFEGEAEQDFAKSEVL 305

  Fly   301 ELGAHLQ-NELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHE 364
            ::..||. :|:.....|||.|||:.||.:|||..|.||.|||:|.:::|||.:  |..|..:|.:
 Worm   306 KVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVDR--ECPDPEVTFD 368

  Fly   365 GIKSLSFMGQVINETLRMHPITPYILRR----TLNDYAVPDHPKYILVKEL----FLIIPTHAIH 421
            .:..|.::..|:.|.||::|:...:..|    |.|          :|..|:    .:.:.|.::|
 Worm   369 QLSKLKYLECVVKEALRLYPLASLVHNRKCLKTTN----------VLGMEIEAGTNINVDTWSLH 423

  Fly   422 HDPDIY-PDPEEFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEYEFS 485
            |||.:: .|..||||:||....:....:|.:..||:|.|.|||::.|.:::::.|..:|..|.|.
 Worm   424 HDPKVWGDDVNEFKPERWESGDELFFAKGGYLPFGMGPRICIGMRLAMMEMKMLLTNILKNYTFE 488

  Fly   486 LNTRKPLINLEDGIALTLMPLGVI 509
             .|.:.:|.|:.....|:.|..|:
 Worm   489 -TTPETVIPLKLVGTATIAPSSVL 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_611004.1	CYP6-like	74..509	CDD:410679	125/478 (26%)
cyp-13A7	NP_496114.1	CYP3A-like	63..507	CDD:410678	125/477 (26%)