Protein Alignment Cyp317a1 and cyp-13A8

DIOPT Version :10

• Sequence 1: NP_611004.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_496115.1
• Gene: cyp-13A8 / 188358
• WormBaseID: WBGene00011674
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 543
• Identity: 137/543 - (25%)
• Similarity: 238/543 - (43%)
• Gaps: 93/543 - (17%)

  Fly    16 LVLLIIAARY--QRDYWRYLDIPHERPKKLW--PIIRQIMTQTLSTEAMKAEHYSAIY---KKFK 73
            |:|:.|...|  ...:|:...:|..     |  ||..:       ..||..:.:...|   |..|
 Worm     5 LILISIVTYYFWHWTFWKRRGLPGP-----WGVPIFGK-------AGAMLEDSFPPGYTLQKWTK 57

  Fly    74 GSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSDPLSGD--------LYALR 130
            ..|...||...:|...:|.|.:|:::|::|.:.||..|      |.:|:.||        :...:
 Worm    58 EYGKIYGFTEGMQKVMVISDPDLVQEILVKQYDNFYGR------KHNPVQGDPDKDKDIHIVGAQ 116

  Fly   131 GESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMRRYVLSSLA 195
            |..||.:|....|:.....:..:...:.:..::|:..:...  |:....|::....:.|....::
 Worm   117 GFRWKRLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREE--SENGKAVNMHLFYQEYTFDVIS 179

  Fly   196 KCVFGLNAEQRKTYPLEDFEQMTELALNSHKHGYLMNLMMI-----RFP---NFCRMLRMRRTPK 252
            :...|....|....||          |...|..:..|...|     .||   :|.:.|.::....
 Worm   180 RVAMGQPDSQMFKNPL----------LKDVKGFFEHNRWQIWMFSGGFPFAVSFLKWLFIKVGKF 234

  Fly   253 QAEEYFI--KLLT----SIVEQRETSGK------PQKDYLQLLIDVKALEFITHQYEADKEL--G 303
            .|..:.:  |.:|    |.:.|||...|      ...||:.:.::.:|  .:.|..|::.|.  .
 Worm   235 GAGPFIVVQKSVTDAVMSRIAQREADKKHGVEPGEAADYIDMFLNARA--EVEHFGESNDEFHKS 297

  Fly   304 AHLQN------ELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHIT 362
            :...|      |:.:...|||.||::.||.:||||.|.|||:|::|.::::||.|  |..:..||
 Worm   298 SSYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVDK--ECPNDEIT 360

  Fly   363 HEGIKSLSFMGQVINETLRMHPITPYI-LRRTLNDYAVPDHPKYILVKELFLIIPTHAIHHDPDI 426
            .:.:..|.:|..||.|:||:.|...:. .||.:.:..:.:.   |:...:.::|.|..:|||.::
 Worm   361 FDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRNTVIGEQ---IVEAGVDVMIDTWTLHHDKNV 422

  Fly   427 Y-PDPEEFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEYEFSLNTRK 490
            : .|.|||||:||..|   |..|..:..||.|.|.|:|::||.|:.:..|:.:|.:|.|..|.:.
 Worm   423 WGNDVEEFKPERWDSP---LTPQQAYLSFGAGPRVCLGMRFALLEQKGLLSHILKKYTFETNAKT 484

  Fly   491 PL-INL-------EDGIALTLMP 505
            .| |.|       .:.:.|:|.|
 Worm   485 QLPIKLVGRATARPENLFLSLKP 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_611004.1	CYP6-like	74..509	CDD:410679	123/478 (26%)
cyp-13A8	NP_496115.1	CYP3A-like	58..500	CDD:410678	120/469 (26%)