Protein Alignment Cyp317a1 and cyp-13A6

DIOPT Version :10

• Sequence 1: NP_611004.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_496113.1
• Gene: cyp-13A6 / 188357
• WormBaseID: WBGene00011673
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 147/564 - (26%)
• Similarity: 254/564 - (45%)
• Gaps: 104/564 - (18%)

  Fly     3 IIFLIIGLLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEHYSA 67
            :||:::..::||:..       |....|.|......:..:.:|.|..:: ||:       :|.:.
 Worm     1 MIFVLLSAVLLGVFT-------YSVWIWSYFIRKGIKGPRGFPGIGMLI-QTI-------DHENP 50

  Fly    68 IYKKF----KGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSDPLSGD--- 125
            .:.|:    |..||..||....|...:|.:.|::.:|..|.|.||..|      |..|:.||
 Worm    51 PFLKYRDWTKQYGPVYGFTEGPQQTMIISEPEMVNEIFKKQFDNFYGR------KLRPIIGDPEK 109

  Fly   126 -----LYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKI 185
                 :::.:|:.||.:|....||...:.:..:.:.:.|...::|..:...:  :.:..:.:..:
 Worm   110 DKRVNIFSTQGKRWKRLRTLSSPSFSNNSLRKVRNSVQECGTEILWNIEQKV--RKNEDIDMLIV 172

  Fly   186 MRRYVLSSLAKCVFGLNAEQRKTYPLEDFEQMTELALNSHKHGYLMNLMMIRFPNFCRMLRMRRT 250
            .:.|.|..:::...|.:.......||   ....:...|...|.:|:..:   ||....:  .|:.
 Worm   173 YQEYTLGVISRIALGQSESNMFKNPL---LPKVQAIFNGSWHVFLITGI---FPPLAGV--FRKM 229

  Fly   251 PKQAEEYFI---KLLTSI-------VEQRETS-------GKPQKDYLQLLIDVKA--LEFITHQY 296
            .|.....||   |:...|       ::||...       |:|| |::.|.:|.:.  ::.::.:.
 Worm   230 SKMLPASFIPAFKIFDLIEVAVQARIDQRAKDEIKGVEPGEPQ-DFIDLFLDARVPDVKILSGEA 293

  Fly   297 EAD----------KELGAHLQNELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVK 351
            ..|          |||   ..:|:.|...|||.||::.||.:|||..|.||.|||:|.:::|||.
 Worm   294 NEDFAKSSVVKINKEL---TFDEIIAQCFVFLAAGFDTTALSLSYATYLLATHPEIQTKLQEEVD 355

  Fly   352 KAIERHDGHITHEGIKSLSFMGQVINETLRMHPI-----TPYILRRTLNDYAVPDHPKYILVKEL 411
            :  |..|..|..:.:..|.::..|:.||||::|:     |...:|.|..:....|....|.|
 Worm   356 R--ECPDPEIFFDHLSKLKYLECVMKETLRLYPLGTTANTRKCMRETTINGVNFDEGMNIQV--- 415

  Fly   412 FLIIPTHAIHHDPDIY-PDPEEFKPDRW-SGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLA 474
                .|..:||:|.|: .|.|:|||:|| :|..:.|:..|::..||.|.|.|||::.||::.::.
 Worm   416 ----DTWTLHHNPRIWGEDVEDFKPERWENGACEHLEHNGSYIPFGSGPRQCIGMRLAQMEQKIL 476

  Fly   475 LALLLSEYEF--SLNTRKP--LINLEDGIALTLMPLGVI---EP 511
            ||.:|.||.|  :.||:.|  |:.     .|||.|..||   ||
 Worm   477 LAQILKEYSFRTTKNTQIPVKLVG-----KLTLSPESVIVKLEP 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_611004.1	CYP6-like	74..509	CDD:410679	129/482 (27%)
cyp-13A6	NP_496113.1	CYP3A-like	61..511	CDD:410678	130/483 (27%)