Protein Alignment Cyp317a1 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_611004.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 528
• Identity: 134/528 - (25%)
• Similarity: 238/528 - (45%)
• Gaps: 69/528 - (13%)

  Fly     1 MWIIFLIIGLLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEH- 64
            |.||||.|...::|:|...:    :...||:...|.....   :||:...:      |.:.:|:
 Worm     1 MAIIFLAILTSIIGVLSFYL----WTWSYWKRRGIAGPSG---YPILGSAL------EMLSSENP 52

  Fly    65 -YSAIYKKFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSDPLSGD--- 125
             |..:.:..|..|...|....|....:|.|.:|::::.:|.:.||..|      |.:|:.||
 Worm    53 PYLQLKEWTKQYGKVYGITEGLSRTLVISDPDLVQEVFVKQYDNFFGR------KLNPIQGDPNK 111

  Fly   126 -----LYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNS-TLMSQPHSTVHIQK 184
                 |::.:|..||.:|....|:...:.:..|...:.|.|.:||..:.. |...||   :.:..
 Worm   112 DKRVNLFSSQGHRWKRLRTISSPTFSNNSLRKLKTTVEECAVELLRHIEQHTDGGQP---IDLLD 173

  Fly   185 IMRRYVLSSLAKCVFGLNAEQRKTYPLEDF------EQMTELALNSHKH---GYLMNLMMIRFPN 240
            ..:.:.|..:.:...|....|....||..:      |....|.|:....   |.::.::|...||
 Worm   174 FYQEFTLDVIGRIAMGQTDSQMFKNPLLPYVRAVFGEPRKGLFLSGSLAPWIGPILRMVMFSLPN 238

  Fly   241 FCR--MLRMRRTPKQAEEYFIKLLTSIVEQRETSGKPQKDYLQLLIDVKALEFITHQYEADKELG 303
            ..:  .:.:.|....|.|..:||..:..:.....|:|| |::.|.:|.|:.:......|...:.|
 Worm   239 IVKNPAVHVIRHTSNAVEQRVKLRMADEKAGIDPGEPQ-DFIDLFLDAKSDDVELENNEDFTKAG 302

  Fly   304 AHLQNELAAHAV-----VFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITH 363
            ..:..:|....:     |||.||::.||.:|||..:.||.||::|.:::||:.:  |..|..:|.
 Worm   303 VKVTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDR--ECADPEVTF 365

  Fly   364 EGIKSLSFMGQVINETLRMHPI-----TPYILRRT-LNDYAVPDHPKYILVKELFLIIPTHAIHH 422
            :.:..|.:|..||.|||||:|:     :...:|.| :.:|.:.:...        ::..|..:|.
 Worm   366 DQLSKLKYMECVIKETLRMYPLGALANSRCCMRATKIGNYEIDEGTN--------ILCDTWTLHS 422

  Fly   423 DPDIY-PDPEEFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEY--EF 484
            |..|: .|.|||||:||....:...::|.:..||:|.|.|||::.|.::.:|.|:.:|.:|  |.
 Worm   423 DKSIWGEDAEEFKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTLEV 487

  Fly   485 SLNTRKPL 492
            ...|:.||
 Worm   488 CNKTQIPL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_611004.1	CYP6-like	74..509	CDD:410679	117/453 (26%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	117/453 (26%)