Protein Alignment Cyp317a1 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_611004.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 535
• Identity: 133/535 - (24%)
• Similarity: 248/535 - (46%)
• Gaps: 86/535 - (16%)

  Fly     2 WIIFLIIGLLVLGLLVLLIIAARYQRDYWRYLDIPHERP-----------KKLWPIIRQIMTQTL 55
            |::.:|       .||||.:...:....::.|.||..:|           |..|
  Rat    12 WLLLVI-------SLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGTILAYRKGFW----------- 58

  Fly    56 STEAMKAEHYSAIYKKFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFW-------NFNDRGL 113
                   |.....:||:   |...|.|...||...|.|.::|:.:::|:.:       ||...|:
  Rat    59 -------EFDKYCHKKY---GKLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFGPVGI 113

  Fly   114 YCNQKSDPLSGDLYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHS 178
            .  :|:..:|.|      |.||.:|..|.|:....::..::..:.:..:  :|..|....|:...
  Rat   114 L--KKAISISED------EEWKRIRALLSPTFTSGKLKEMFPIINQYTD--MLVRNMRQGSEEGK 168

  Fly   179 TVHIQKIMRRYVLSSLAKCVFGLNAEQRKTYPLEDF-EQMTELALNSHKHGYLMNLMMIRF--PN 240
            ...::.|...|.:..:....||:|.:.... |.:.| |::.:|..........:::.:..|  |.
  Rat   169 PTSMKDIFGAYSMDVITATSFGVNVDSLNN-PQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPL 232

  Fly   241 FCRMLRMRRTPKQAEEYFIKLLTSIVEQRET----SGKPQKDYLQLLIDVKALEFITHQYEADKE 301
            | ..|.:...|:...::|   .||:...:|.    ..|.:.|:|||:|:.:..: :...::|..:
  Rat   233 F-EALNVSMFPRDVIDFF---KTSVERMKENRMKEKEKQRMDFLQLMINSQNSK-VKDSHKALSD 292

  Fly   302 LGAHLQNELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGI 366
            :      |:.|.:|:|:.||||.|::.||:|||.||:||::|.::::|:..|:. :..|.|::.:
  Rat   293 V------EIVAQSVIFIFAGYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALP-NKAHATYDTL 350

  Fly   367 KSLSFMGQVINETLRMHPITPYILRRTLNDYAVPDHPKYILVKELFLIIPTHAIHHDPDIYPDPE 431
            ..:.::..|:|||||::||...:.|....|..:..   ..:.|...::|||.|:|.||..:|:||
  Rat   351 LQMEYLDMVVNETLRLYPIAGRLERVCKTDVEING---VFIPKGTVVMIPTFALHKDPHYWPEPE 412

  Fly   432 EFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEYEFSLNTRKPLINLE 496
            ||:|:|:|...........:..||.|.|:|||::||.:.:::||..:|..:.|     :|.  .|
  Rat   413 EFRPERFSKKNQDNINPYMYLPFGNGPRNCIGMRFALMNMKVALVRVLQNFSF-----QPC--KE 470

  Fly   497 DGIALTLMPLGVIEP 511
            ..|.|.|...|:::|
  Rat   471 TQIPLKLSKQGLLQP 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_611004.1	CYP6-like	74..509	CDD:410679	117/448 (26%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	119/455 (26%)