Protein Alignment Cyp317a1 and cyp3a5

DIOPT Version :10

• Sequence 1: NP_611004.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: XP_012819594.1
• Gene: cyp3a5 / 100037874
• XenbaseID: XB-GENE-5821575
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 531
• Identity: 142/531 - (26%)
• Similarity: 248/531 - (46%)
• Gaps: 81/531 - (15%)

  Fly    10 LLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEHYSAIYKKFKG 74
            |||| ||.||...|.:....::...||...|   .|.|...    |.......|.....:||:
 Frog    14 LLVL-LLTLLAYYAIWPYKLFKRYGIPGPTP---IPFIGTF----LGNRHGLMEFDMECFKKY-- 68

  Fly    75 SGPFCGFYALLQPRALILDRELIRQIMIKD----FWNFNDRGLYCNQKSDPLSGDLYALRGESWK 135
             |...|.|...:|...|:|..:|:.||:|:    |.|..|.||     |.||...:...:.|.||
 Frog    69 -GKVWGIYEGQKPLLAIVDPVIIKSIMVKECYTNFTNRRDFGL-----SGPLKSSVLISKDEQWK 127

  Fly   136 EMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMRRYVLSSLAKCVFG 200
            .:|..|.|:....::..::..:....|.|:..::..:.::  ..:.::.|...|.:..:....|.
 Frog   128 RIRTVLSPTFTSGKLKQMFPLMNHYGELLVKNIHKKINNK--EPLDMKHIFGSYSMDIVLSTSFS 190

  Fly   201 LNAEQRKTYPLEDFEQMTELALNSHKHGYLMNLMMIRF-----------PNFCRMLRMRRTPKQA 254
            :|.:.... |.:.|  :|. |.|.....:...|.:|..           .||| .|.::     .
 Frog   191 VNVDSMNN-PNDPF--VTN-ARNLFTFSFFNPLFLISILCPFLVPLLDKMNFC-FLSLK-----I 245

  Fly   255 EEYFIKLLTSIVEQRET-SGKPQKDYLQLLIDVKALEFIT------HQYEADKELGAHLQNELAA 312
            ..:|...:.||.::|:. :.:.:.|:|||::|.::.|..:      |.|   |||.   ..|:.|
 Frog   246 LNFFKDAVASIKKKRQKGTHEDRVDFLQLMVDAQSNEGKSVPEEEKHGY---KELS---DTEILA 304

  Fly   313 HAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFMGQVIN 377
            .:::|:.||||.|:.||.::.|.:|.||::|.::.||: .|:..:....|::.:..:.:|..|||
 Frog   305 QSLIFIMAGYETTSTTLMFLAYNIATHPDVQRKLEEEI-DALLPNKAPPTYDALMKMEYMDMVIN 368

  Fly   378 ETLRMHPITPYI-----LRRT--LNDYAVPDHPKYILVKELFLIIPTHAIHHDPDIYPDPEEFKP 435
            |:|||.|  |.|     .::|  :|...:|        ..:.:::|..|:|.:|:|:|:||||:|
 Frog   369 ESLRMFP--PAIRIDRVCKKTMEINGVTIP--------AGVVIVVPLFALHLNPEIWPEPEEFQP 423

  Fly   436 DRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEYEFSLNTRKPLINLEDGIA 500
            :|:|......|:...:..||||.|:|||::||.:.:::||.:||.  .|.|.|.|     :..:.
 Frog   424 ERFSKENQKNQDPYNFLPFGVGPRNCIGMRFALVNMKVALTILLQ--NFRLETCK-----DTPVP 481

  Fly   501 LTLMPLGVIEP 511
            |.:...|.::|
 Frog   482 LKICTKGYLKP 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_611004.1	CYP6-like	74..509	CDD:410679	123/463 (27%)
cyp3a5	XP_012819594.1	cytochrome_P450	67..498	CDD:477761	125/470 (27%)