Protein Alignment Cyp6a8 and cyp3c1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_997838.1
• Gene: cyp3c1 / 324340
• ZFINID: ZDB-GENE-030131-3060
• Length: 505
• Species: Danio rerio
• Alignment Length: 514
• Identity: 154/514 - (29%)
• Similarity: 261/514 - (50%)
• Gaps: 56/514 - (10%)

  Fly     1 MALTYILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNK 65
            :::|:.|..:.:.||.|...:.|   .:||:.|||...|....|.  .|..:|.|.....:...|
Zfish     7 LSVTWTLVVLVITLLLIYGVWPH---GFFKKLGIPGPRPLPFVGT--ALSYSKGICNFDIECSKK 66

  Fly    66 FRESKAPFVGFFFFQSPAAFVIDLELAKQILIKD-FSNFSNKGIFYNEKDDPISAHLFNLDGAQW 129
            :    ....|.:..:.|...|.|||:.|.||:|| :|.|:|:.....:...|.:..:..:...:|
Zfish    67 Y----GKVWGIYDGRLPLLLVTDLEMIKTILVKDCYSTFTNRRNMNPDLVGPFADGITLVKDERW 127

  Fly   130 RLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGTCAFGI 194
            |.:|:.||..||||::|.::|..::.|:.|:..|.:|.| |..|:|:|:||.:::||:.:.:|.:
Zfish   128 RRIRSSLSPYFTSGRLKEIFPIAMTHADRFIKNMEKKDP-NLPLKIKDVVAPYSLDVVASSSFSV 191

  Fly   195 QCNSLRDEKAEFL-----YFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIV 254
            ..:|:.:....|:     :|....|...   .||..|..|...|..|:|:...:....:||.:.:
Zfish   192 DFDSINNPDDPFVTSIKSFFNINPLSPL---FLLLAFCPSAANLLAKMGISVFSRSTTDFYYKAL 253

  Fly   255 TETVAVREKEHIKRN---DFMDMLIELKNQ------KEMTLENGDVVRGLTMEEVLAQAFVFFIA 310
            .:.    :.||.:.|   ||:.::|:  ||      |:...|  ..|:|||..|:|:|:|:|.:.
Zfish   254 RKI----KDEHNESNGRVDFLKLMIQ--NQIPDDQVKDTASE--QPVKGLTDHEILSQSFIFILG 310

  Fly   311 GFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNF------TYECTKDLKYLNQVLDET 369
            |:||:|:|:.:.||.||.|||.       :|:::|:.|:||      ||:....:.||...:.|:
Zfish   311 GYETTSTTLSYLLYNLATNPDC-------LEKLVEEIDKNFPLDIPITYDALMRMDYLEMAIHES 368

  Fly   370 LRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESA 434
            :|::...|.|:|:..|...:.|   ..|.....|.||...:..||.::..|.||:|||||||...
Zfish   369 MRVFPAGPRLERVCKKTVEING---ITIPKNTLVGIPLYVLSRDPDLWESPNEFKPERFSPESKT 430

  Fly   435 GRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPL----VYDPK 489
            .....|::|||.|||||||:||..|..::.:..|::.:...||.:|..|:    .:.||
Zfish   431 EINQCAFMPFGLGPRNCIGMRFALMMMKLLVVKLLQKYTVETCKETQIPVQLNFFFQPK 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	137/445 (31%)
cyp3c1	NP_997838.1	cytochrome_P450	66..495	CDD:477761	138/450 (31%)