Protein Alignment Cyp6a23 and Cyp4e3

DIOPT Version :10

• Sequence 1: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 558
• Identity: 129/558 - (23%)
• Similarity: 247/558 - (44%)
• Gaps: 96/558 - (17%)

  Fly     1 MSLLLTLIALLVSLLLFMARRRHGYWQRRGIPHD----VPHPIYGNMKDWPKK-RHIAMIFRDYY 60
            :::|..|:..|::|:.|..:..    |||.:..:    .|.||.||.....|. ..|...|.|::
  Fly     3 LAVLALLVLPLITLVYFERKAS----QRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFDWW 63

  Fly    61 TKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQK 125
            ..|.:..:.   |:..::...|:|:.:.::.:|  :......:...|:.:...|...|.:..|.|
  Fly    64 YDYGKDNFL---FWIGYSSHIVMTNPKQLEYIL--NSQQLIQKSTIYDLLHPWLGHGLLTSFGSK 123

  Fly   126 WRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFS--AKTTTGEGQVLEIVDLV--ARY-TADV 185
            |...|..:||:|....:::...:   :.|...|..:  .|.:.|:    .|:|..  |.| |.||
  Fly   124 WHKHRKMITPSFHFNILQDFHEV---MNENSAKFMTQLKKASAGD----TIIDFQEHANYLTLDV 181

  Fly   186 IGNCAFGLNCNSLQNPNAEFV--------TIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKLNV 242
            |.:.|.|:..|:::..::..|        .|..||....:....:..|...|....:.|:
  Fly   182 ICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLK----- 241

  Fly   243 QDVEDFYTSIVRNTIDYRLRTNEKRHD-----------FMDSLIEMYEKEQAGNTEDG--LSFNE 294
             .::||...|:...: |.|:....:.|           |:|:|:        .:|.||  |:..|
  Fly   242 -TLQDFTYDIIEKRV-YALQNGGSKEDHDPSLPRKKMAFLDTLL--------SSTIDGRPLTRQE 296

  Fly   295 ILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKH-NNEFTYEGIKEMKYLE 358
            |..:...|...|.:|:::.:.|::|.|:...|:|.:|..|...|:... |...:::.|.:||||:
  Fly   297 IYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLD 361

  Fly   359 QVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFT 423
            ..:.|..|.||.:..:.|....|:.....  .:.||||:.:..:.:.|:..|:.:|..|:||||.
  Fly   362 LFIKEAQRVYPSVPFIGRYCDKDYDINGS--IVPKGTTLNLALILLGYNDRIFKDPHHFRPERFE 424

  Fly   424 DEAIAARPS-CTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKF------SVSTETQIPM--- 478
            :|    :|: ..:|||..|||||||.:|.|::....::.::|.::.      .|||:.::..
  Fly   425 EE----KPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLG 485

  Fly   479 --------------KF--VVKSIL-LSAENGIHLKVEK 499
                          |:  ::.::| |.::||:||::.:
  Fly   486 LAPDEKLKREAGRHKYDPILSAVLTLKSDNGLHLRLRE 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	109/479 (23%)
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	109/483 (23%)