Protein Alignment Ciao1 and ciao-1

DIOPT Version :10

• Sequence 1: NP_610996.1
• Gene: Ciao1 / 36655
• FlyBaseID: FBgn0033972
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_493247.2
• Gene: ciao-1 / 173152
• WormBaseID: WBGene00012479
• Length: 337
• Species: Caenorhabditis elegans
• Alignment Length: 345
• Identity: 145/345 - (42%)
• Similarity: 201/345 - (58%)
• Gaps: 22/345 - (6%)

  Fly     1 MGRLILEHTLQGHK---GRIWGVAWHPKGNVFASCGEDKAIRIWSLTGNTWS-----TKTILSDG 57
            |.|.|.|...||.|   .|:|...||..|.:.||||:|||:|:|||.|...|     .:|.|.|.
 Worm     1 MLRQIGEFYHQGEKDDTSRVWMTCWHHGGRILASCGDDKAVRVWSLVGEPDSKMRLECRTTLDDS 65

  Fly    58 HKRTIREIRWSPCGQYLASASFDATTAIWSKSSGEFECNATLEGHENEVKSVSWSRSGGLLATCS 122
            |.|.:|.:.:|..|:.|.||||||:..::.:..|||.....|||||:|||...:|:|...|||||
 Worm    66 HTRAVRSVAFSNDGKCLVSASFDASVVVYQQEDGEFAEVNKLEGHESEVKCAVFSKSDEFLATCS 130

  Fly   123 RDKSVWIWEVAGDDEFECAAVLNPHTQDVKRVVWHPTKDILASASYDNTIKMFAEEPIDNDWDCT 187
            ||||||.|:...|::|..:::|.|||||||:|.||||:|:|.|.|||::|:.:..:  ..||...
 Worm   131 RDKSVWFWQQDEDEDFSVSSILQPHTQDVKQVAWHPTEDLLVSCSYDSSIRFYRFD--GEDWVTQ 193

  Fly   188 ATLTS-HTSTVWGIDFDADGERLVSCSDDTTIKIWRAYHPGNTAGVATPDQQTVWKCVCTVSGQH 251
            ..:.. |..|||.|.||.:|.|||:..:|..|:::...:.|:.:.    ||.| ||.|.....::
 Worm   194 QKIDGCHVGTVWSIAFDTEGHRLVTVGEDHCIQLFVRENIGSKSA----DQDT-WKSVARYDVEN 253

  Fly   252 SR-AIYDVSWCKLTGLIATACGDDGIRIFKESSDSKPDEPTFEQITAEEGAHDQDVNSVQW--NP 313
            :| .:|.|:|.....:|||..||..||:||.|  |.|:.|..|.: ...|.|:.|||.|.|  ||
 Worm   254 TRWPLYSVAWNSTNDVIATGGGDCKIRLFKIS--STPESPVIEHL-GVVGRHELDVNHVAWNPNP 315

  Fly   314 VVAGQLISCSDDGTIKIWKV 333
            ..:..|.|.||||||::|::
 Worm   316 KFSNLLTSASDDGTIRLWEL 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ciao1	NP_610996.1	WD40	6..332	CDD:238121	141/337 (42%)
		WD40 repeat	17..57	CDD:293791	19/44 (43%)
		WD40 repeat	63..101	CDD:293791	14/37 (38%)
		WD40 repeat	106..145	CDD:293791	18/38 (47%)
		WD40 repeat	152..191	CDD:293791	15/38 (39%)
		WD40 repeat	197..248	CDD:293791	18/50 (36%)
		WD40 repeat	255..299	CDD:293791	17/43 (40%)
		WD40 repeat	306..331	CDD:293791	14/26 (54%)
ciao-1	NP_493247.2	WD40	<17..336	CDD:441893	138/329 (42%)
		WD40 repeat	25..64	CDD:293791	18/38 (47%)
		WD40 repeat	71..109	CDD:293791	14/37 (38%)
		WD40 repeat	114..153	CDD:293791	18/38 (47%)
		WD40 repeat	160..197	CDD:293791	15/38 (39%)
		WD40 repeat	204..250	CDD:293791	18/50 (36%)
		WD40 repeat	258..300	CDD:293791	17/44 (39%)
		WD40 repeat	306..333	CDD:293791	14/26 (54%)