Protein Alignment SMC2 and TTN7

DIOPT Version :10

• Sequence 1: NP_610995.1
• Gene: SMC2 / 36653
• FlyBaseID: FBgn0027783
• Length: 1179
• Species: Drosophila melanogaster
• Sequence 2: NP_180285.4
• Gene: TTN7 / 817259
• AraportID: AT2G27170
• Length: 1204
• Species: Arabidopsis thaliana
• Alignment Length: 1307
• Identity: 312/1307 - (23%)
• Similarity: 581/1307 - (44%)
• Gaps: 264/1307 - (20%)

  Fly     1 MYVKKLVLDGFKSYGRRTEIEGFDPEFTAITGLNGSGKSNILDSICFVLGISNL-QNVRASALQD 64
            |::|:::::|||||..:...|.|..:...:.|.|||||||...:|.|||  |:: ||:|:.....
plant     1 MFIKQVIIEGFKSYKEQVATEEFSNKVNCVVGANGSGKSNFFHAIRFVL--SDIYQNLRSEDRHA 63

  Fly    65 LVYKNGQAGITKATVTIVFDNTNPAQCPQGYEKCREISVTRQVVVGGKNKFLINGKLVQNKKVQD 129
            |:::.....:..|.|.|||||:: .:.|...|:.|    .|:.|...|:.:.::||.:...:|.:
plant    64 LLHEGAGHQVVSAFVEIVFDNSD-NRFPVDKEEIR----LRRTVGLKKDDYFLDGKHITKGEVMN 123

  Fly   130 FFCSIQLNVNNPNFLIMQGKIQQVLNMKPKEVLSMVEEAAGTSQYKTKRDATKTLIEK---KETK 191
            ...|...:..||.:::.||||..:..||..|.|.:::|..||..|:.:|..:..::::   |..:
plant   124 LLESAGFSRANPYYVVQQGKIASLTLMKDIERLDLLKEIGGTRVYEERRRESLRIMQETGNKRKQ 188

  Fly   192 VRETKVLLDEEVLPKLVKLRQERSAYQEYQKICRDIDFLI---RIHISAKYLKQCETLKTVEANE 253
            :.|....|||. |.:|.:.::|...||:..|..:.:::.|   .:|.:.:.|:|.|..:|..:.|
plant   189 IIEVVHYLDER-LRELDEEKEELRKYQQLDKQRKSLEYTIYDKELHDAREKLEQVEVARTKASEE 252

  Fly   254 H-KIEDRIANCKATHAKNLAEVESIENSVKEMQQQIDAEMGGSIKNLETQLSAKRALEATATGSL 317
            . |:.||:       .|...:.:|::.|:||:           .|.|:|....|..:||..|.:|
plant   253 STKMYDRV-------EKAQDDSKSLDESLKEL-----------TKELQTLYKEKETVEAQQTKAL 299

  Fly   318 KAAQGTIQQDEKKIR------MASKN-----IEDDERALAKKEADMAKVQGEFESLKEADARDSK 371
            | .:..::.|.|..:      :.|||     :...||.:.....::..::..:||..:.:.:.||
plant   300 K-KKTKLELDVKDFQDRITGNIQSKNDALEQLNTVEREMQDSLRELEAIKPLYESQVDKENQTSK 363

  Fly   372 AYEDAQKKLEAVSQGLSTNENGEASTLQEQLIVAKEQFSEAQTTIKTSEIELRHTRGVLKQREGE 436
            ...:.:|.|..:.|     :.|.|:           |||......|....|:...:.||
plant   364 RINELEKTLSILYQ-----KQGRAT-----------QFSNKAARDKWLRKEIEDLKRVL------ 406

  Fly   437 TQTNDAAYVKDKKLHDQLV---VEIKNLERQLQSLDYEGGHFE----------KLKQRRNDLHMR 488
                |:..|:::||.|:::   .::...:..::..:.|.|..|          ..|:|..|...|
plant   407 ----DSNTVQEQKLQDEILRLNTDLTERDEHIKKHEVEIGELESRISKSHELFNTKKRERDEEQR 467

  Fly   489 KR---------------DLKRELDRCNASRYDLQYQDPEP-----NFDRR-----KVRGLVGKLF 528
            ||               .||.||:|   ::.:|.:..|..     |..||     ::.|:.|.|.
plant   468 KRKEKWGEESQLSSEIDKLKTELER---AKKNLDHATPGDVRRGLNSIRRICADYRINGVFGPLV 529

  Fly   529 QVKDMQNSM--ALVQTAGGSLYSYVTDDDVTSKKILQRGNLQR--RVTLIPINKIQSGSLNRNVV 589
            ::.|.....  |:..|||.||::.|.::|..|.||::..|..:  |||.:|:|:|::..:|
plant   530 ELVDCDEKFFTAVEVTAGNSLFNVVVENDDISTKIIRHLNSLKGGRVTFLPLNRIKAPRVN---- 590

  Fly   590 EYAQNKVGAENVQWAMSLIDYDRYYEPVMKFCFGGTLICKDLIVAKQISYDPRINCRSVTLEGDV 654
             |.::.....    .:..:.:|..:||.:...||.|::|:||.||.:::.:..::|  :|:|||.
plant   591 -YPKDSDAIP----LLKKLKFDSKFEPALGQVFGRTVVCRDLNVATRVAKNDDLDC--ITMEGDQ 648

  Fly   655 VDPHGTVSGGAAPKGANVLEELHAIKQIEKEYREIDSEIAQVEKQIASIENQALAFNKMKENLDL 719
            |...|.::||......:.|..::.|.|..|...|.:.|:..|.:|:..|:.|.......::.|:.
plant   649 VSRKGGMTGGFYDHRRSKLRFMNIIMQNTKSINEKEKELEDVRRQLQVIDQQITQLVTEQQRLEA 713

  Fly   720 RQHELTMCENRLAQTTFQQNQAEIEEMRERVKTLEQQ------IIDSREK------------QKT 766
               :.|:|            :.::|::::.:....:|      .|:.:||            :.:
plant   714 ---DWTLC------------KLQVEQLKQEIANANKQKHAIHKAIEYKEKLLGDIRTRIDQVRSS 763

  Fly   767 SQAKIVDIEAKLADAKGYRERE----LNAATNEIKVTKQRAEKSRANWKKREQEFE-----TLQL 822
            ...|..::..:|.|.....|||    ||....::|..|...:..|...:.|:.|.|     .|:.
plant   764 MSMKEAEMGTELVDHLTPEEREQLSKLNPEIKDLKEKKFAYQADRIERETRKAELEANIATNLKR 828

  Fly   823 EITELQKSIETAKKQHQEMIDNLEKFKAELDALKVNSSSAASEV----------TELEQAIKEQK 877
            .|||||.:|  |......:..:....:.|||..|::.:.||.|:          |:..:.||::|
plant   829 RITELQATI--ASIDDDSLPSSAGTKEQELDDAKLSVNEAAKELKSVCDSIDEKTKQIKKIKDEK 891

  Fly   878 DKLRDQNKEMRNQLVKKEKMLKENQEIELEVKKKENEQKK-------ISSDAKEAKKRMEALEAK 935
            .||:....:.:..|...:|.|:|...:...:..|::|..|       :||||.:..||
plant   892 AKLKTLEDDCKGTLQDLDKKLEELFSLRNTLLAKQDEYTKKIRGLGPLSSDAFDTYKR------- 949

  Fly   936 YPWIPEEKNCFGMKNTRYDYSKEDPHEAGNKLAKMQEK-KDKMERTLNMNAIMVLDRE---EENF 996
                         ||.:             :|.||..: .:::::..::|. ..||:.   .|..
plant   950 -------------KNIK-------------ELQKMLHRCSEQLQQFSHVNK-KALDQYVNFTEQR 987

  Fly   997 KETERRRNIVAMDKEKIKKIIVKMDEEEQDQLNKAATEVNTNFSGIFSSLLP------------- 1048
            :|.:.|:..:....||||::|..:|:.:.:.:.:....|..:|..:||.|:.
plant   988 EELQNRQAELDAGDEKIKELITVLDQRKDESIERTFKGVAHHFRDVFSELVQDGYGNLIIMKKKD 1052

  Fly  1049 -------------GAEAKLNPVHTNGCL---TGLEIKVGFNGIWKESL-GELSGGQKSLVALSLV 1096
                         |.||.     |.|.:   .|:::||.|.|..:..| .:||||||::|||:|:
plant  1053 LDNDDEDDDDDDGGREAV-----TEGRVEKYIGVKVKVSFTGQGETQLMKQLSGGQKTVVALALI 1112

  Fly  1097 LAMLKFSPAPLYILDEVDAALDMSHTQNIGSMLKQHFTN--SQFLIVSLKDGLFNHANVLFRTLF 1159
            .|:.:..|||.|:.||:|||||..:...:|:::::...:  :||:..:.:..|...|:.::....
plant  1113 FAIQRCDPAPFYLFDEIDAALDPQYRTAVGNLIRRLADDYGTQFITTTFRPELVRVADKIYGVFH 1177

  Fly  1160 EEGVSTI 1166
            :..||.:
plant  1178 KNRVSIV 1184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMC2	NP_610995.1	SMC_N	2..1162	CDD:481474	309/1300 (24%)
TTN7	NP_180285.4	SMC_N	2..1175	CDD:481474	309/1295 (24%)