DRSC/TRiP Functional Genomics Resources

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Protein Alignment NaPi-T and Slc17a8

DIOPT Version :10

Sequence 1:NP_525116.2 Gene:NaPi-T / 36651 FlyBaseID:FBgn0016684 Length:524 Species:Drosophila melanogaster
Sequence 2:NP_714947.1 Gene:Slc17a8 / 266767 RGDID:628870 Length:588 Species:Rattus norvegicus


Alignment Length:513 Identity:149/513 - (29%)
Similarity:252/513 - (49%) Gaps:61/513 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 VEARTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLER 68
            :..|.::..|:.:||.:::.||.||.:.||:|:            .|||                
  Rat    72 IPKRYIIAVMSGLGFCISFGIRCNLGVAIVEMV------------NNST---------------- 108

  Fly    69 WFLDWANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCCF 133
            .::| .....:...|:|:.:..|.:.|||||.:...|||||.::.|:....|||.:..:......
  Rat   109 VYVD-GKPEIQTAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKFAANRVFGAAIFLTSTLNM 172

  Fly   134 LIPIVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKF-VSAYLGSSVGVALFYPI 197
            .||..:...|..::.:|:.||.:.|:.:|:.|.:.:||.||.|||:. .:::.||..|..:..|:
  Rat   173 FIPSAARVHYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPL 237

  Fly   198 FGYIIDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLG-----ASIQG 257
            .|.::.:..|..|:||.|:.|.:|::.|....::.||.||.|::.||.:||.|:|     ||:  
  Rat   238 AGVLVQYIGWASVFYIYGMFGIIWYMFWLLQAYECPAVHPTISNEERTYIETSIGEGANLASL-- 300

  Fly   258 SKGPTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRML 322
            ||..|||:...||.||:..:||.:...|..:.|:...|.||..:..:.|...|.||.:||::..:
  Rat   301 SKFNTPWRRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTI 365

  Fly   323 FAYVFSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIVLALAYFGYNAT--AAIVLVTVATMLH 385
            ...:....||||.....::.|.|||:..   ||..|:....|...|::.|  .||..:.:|....
  Rat   366 VVPIGGQLADYLRSRKILTTTAVRKIMN---CGGFGMEATLLLVVGFSHTKGVAISFLVLAVGFS 427

  Fly   386 GAVSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTSLML 450
            |...||...:.:|::|.||.|::|:|..:|.:.|.:.|.|||.:| .::|.:.|:||||:.:|:.
  Rat   428 GFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMT-KHKTREEWQNVFLIAALVH 491

  Fly   451 TGSGILYVLFSESKLQPWNSGCHQLPDSGLKELQNLGR------DQDDEEEKKPLKSD 502
            ....|.|.:|:..:.|.|            .:.:||..      |||:..|:..|..:
  Rat   492 YSGVIFYGVFASGEKQDW------------ADPENLSEEKCGIIDQDELAEETELNHE 537

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NaPi-TNP_525116.2 2A0114euk 1..474 CDD:129972 142/477 (30%)
Slc17a8NP_714947.1 MFS_SLC17A6_7_8_VGluT 79..502 CDD:340940 138/457 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 539..588
Blue background indicates that the domain is not in the aligned region.

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