DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and Slc17a3

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	XP_006254003.1	Gene:	Slc17a3 / 266730	RGDID:	628815	Length:	538	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	133/473 - (28%)
Similarity:	216/473 - (45%)	Gaps:	41/473 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 MTFIGFIVNY-MIRIN--LNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLERWFLDWA 74
            :.||..|.|: :|..|  ::||:|.|:..    |...:|.||:              ..||.|..
  Rat    81 IAFIAHICNFTLIAQNSIISITMVAMVNN----TDQPSHLNSS--------------TEWFPDGL 127

  Fly    75 N---------IPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFG---WSNGI 127
            |         :..:...::|:.:.||.:..|..:....:|.|||.||.|.|||.|.|   ..:.:
  Rat   128 NGDQHEASKHLSIKAPVYNWSPQTQGIIFSSVQYGMMLMQGPGGYLAGKLGTKKVVGIALLGSSL 192

  Fly   128 GVFCCFLIPIVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVS-AYLGSSVGV 191
            ...|   ||:.:......|:..|..||...|..:.....|..||.||||||:..| |..|..:|:
  Rat   193 LTLC---IPLAANLGLAFLLATRAVQGLTQGAGYGGQFALWQKWAPPNERSRLCSIAMSGMILGI 254

  Fly   192 ALFYPIFGYIIDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQ 256
            .....:.|.|.:...|.:|:||.|.:|.:..:.|..||:|.|..||.|:..|:::|..||.....
  Rat   255 FAVLLVGGIISEALGWPFVFYIFGSIGVVCCLLWLILVYDDPVSHPWISSPEKEYILSSLDQQFN 319

  Fly   257 GSKGPTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRM 321
            ..:.|.|.||:..|.|:|...:......|.:.||:.:.|||...:...|||..|.||.||..:..
  Rat   320 SEEQPLPIKAMLKSLPLWSMCLCSMTHQWLVNTLIIYTPTYISSVFKVNIRDNGLLSSLPFFVAW 384

  Fly   322 LFAYVFSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIVLALAYFGYNATAAIVLVTVATMLHG 386
            :...:..:.||:|| :.......|||:.|.:.......:|:||.|...:..|....:|::..|..
  Rat   385 VIGILGGLLADFLL-SKNFRLITVRKIITILGNTPPAALVVALPYVQSSYIATTTFLTLSCGLSP 448

  Fly   387 AVSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKN-VFLLTSLML 450
            ...||...:.:|::|.||.:::|.|..:......:.|.:.|... |..:...|:| .|:|.::.|
  Rat   449 LCQSGVYINALDIAPRYASLLMGTSRGLAHSSAVMVPIVAGFFL-NQDSEFGWRNFFFVLFAINL 512

  Fly   451 TGSGILYVLFSESKLQPW 468
            .|. |:|::|:::.:|.|
  Rat   513 FGL-IIYLVFAKADIQEW 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	133/473 (28%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	112/388 (29%)
Slc17a3	XP_006254003.1	2A0114euk	71..537	CDD:129972	133/473 (28%)
Slc17a3	XP_006254003.1	MFS	145..522	CDD:119392	112/382 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820