DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and slc-17.8

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001023848.1	Gene:	slc-17.8 / 179234	WormBaseID:	WBGene00017798	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	504	Identity:	121/504 - (24%)
Similarity:	219/504 - (43%)	Gaps:	65/504 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 YMIRINLNITIVDMIAGKGAITSNETH-ENSTDLAALAEMNERFSLERWFLDWANIPYEKNGFHW 85
            :::..|:.:.||.|: ...|...|||: ||:..|                |||::
Worm    68 HLMNSNMGMAIVCMV-NSSATYDNETYPENAAPL----------------LDWSS---------- 105

  Fly    86 NEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCCF----LIPIVSYWSYTGL 146
              .:||.:..:|......:...|| :|.|:..|.:...|..|.....|    :.||..||:
Worm   106 --DEQGYIFSAFNAGLLVMLFTGG-MADKFNAKYMILVSVAIASLANFTLPWMAPISVYWA---- 163

  Fly   147 IILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVS-AYLGSSVGVALFYPIFGYIIDWTR---- 206
            |..|...|:...|..|:|:.|..:|.|.:|||..:. |..|..:|..:..|..|.:...|.
Worm   164 IFSRFLVGFADALLQPAMNSLITRWFPTSERSYALGLATGGRQIGTLIIIPAAGALCSQTEIFGG 228

  Fly   207 WEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQGSK---GPTPWKAIA 268
            |..::|:.|.:|.|:..::.||..|.|::...|:|:|.|||..|..:...|.|   ...|||.|.
Worm   229 WPSIFYLSGFIGVLFIFSYIFLGADKPSKQSCISDNELKFITISNQSEDVGKKRTERKVPWKNIL 293

  Fly   269 TSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRMLFAYVFSIFAD- 332
            .|..||.:|::.....:.|.||:...|:|...:||::....|.||.|| .:.:.||.:.|.:.:
Worm   294 KSGAVWASVISLVCHEFPLMTLIMFLPSYLHDVHHYHSTENGILSALP-TVSLWFAKIGSSYLNT 357

  Fly   333 YLLRTDKMSRTNVRKLATFICCGTKGLIVLALAYF-GYNATAAIVLVTVATMLHGAVSSGPLASM 396
            :|.:.....:..:.|:...|.....|:.:||..:. ..:|..|::.:.::....|..:.|...::
Worm   358 WLQKNTTWKKDTICKVLNSIGSIGLGVFLLAATFLDNEHAWMAVLFLCLSMASAGLHTPGCQLAL 422

  Fly   397 VDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTSLMLTGSGILYVLFS 461
            |.::|.|:|.|.|.:.....:.|.|.| |:.::...::|...|..||.:::::.....|::.::.
Worm   423 VSVAPAYSGAVTGFTFFFVAVSGIIHP-IITKMIVKDRTAAEWNLVFYISTVIAIFPIIIFNVWG 486

  Fly   462 ESKLQPWNSGCHQLPDSGLKELQNLGRDQDDEEEKKPLKSDHDKETPIV 510
            .:::|.|              .::....|.:...||..||.....:|.:
Worm   487 STEVQWW--------------AKSKASMQQEPNNKKMSKSSKASSSPSI 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	115/466 (25%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	99/397 (25%)
slc-17.8	NP_001023848.1	MFS_SLC17	57..486	CDD:340876	113/453 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020