DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and Y4C6B.4

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_741396.1	Gene:	Y4C6B.4 / 177312	WormBaseID:	WBGene00021158	Length:	458	Species:	Caenorhabditis elegans

Alignment Length:	496	Identity:	112/496 - (22%)
Similarity:	201/496 - (40%)	Gaps:	77/496 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLERWFLDW 73
            :|.:|..:....||:|   :|.|.:.|               ..||:...|:|...   :...|:
Worm    15 LLSFMCLVSVCSNYII---INFTFICM---------------KDDLSQTTEVNGTL---KSIYDY 58

  Fly    74 ANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCCFLIPIV 138
            .  |.||....| ....|.::|:|         |..||..|||.::.|..:..:......|.|..
Worm    59 T--PTEKKYILW-AVAFGTMVGTF---------PINILYVKYGARIPFFSAGVLSAVTTGLTPWA 111

  Fly   139 SYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVSAYLG-SSVGVALFYPIFGYII 202
            :..|....:.||..||......:.::.::.:||.|.:|.:.|::.... :|:...:.....|.|.
Worm   112 AAQSMWIFVALRFLQGVAYSADFAAIGIVISKWAPLDETAIFIATLTSFTSIASIITNGASGVIC 176

  Fly   203 DWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLG-ASIQ-GSKGPTPWK 265
            |...|:|.:|.......|.|..|..:..|.|..|..::..|..:|:|:.. |.|: |.|  .|:|
Worm   177 DTLGWQWSFYFHSATCLLIFCCWVLIYQDDPTFHKSVSVKELGWIQKNKSEAHIKVGMK--VPYK 239

  Fly   266 AIATSRPVWLNV-VAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRMLFAYVFSI 329
            ||.|| ||.|.| :..:..:..|..:.|:.|.|||.:..::|:..||..|:...:.:.|.:|.:.
Worm   240 AIFTS-PVVLTVWLCAFTELSTLILIATYGPIYFRSVLGFDIKIIGFYLGIMIAIHLPFRFVCAF 303

  Fly   330 FADYLLRTDKMSRTNV-RKLATFICCGTKGLIVLALAYFG-----YNATAAIVLVTVATMLH--- 385
            .:|......:|.:.:: ..||.       |.:.::...||     :|.:|.:.|..:...:.
Worm   304 LSDKTKCISEMGKIHIFNTLAV-------GFVGISFLIFGKIPPEHNISAVVCLAILECFISFNS 361

  Fly   386 ------GAVSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFL 444
                  |.:.:...:|:|..:..:...:...||     |..::.|:..:   :|||  .|.:||:
Worm   362 GGFYKCGTLHARQFSSIVISAIQFTKCISLFSG-----PALVAFFVTDE---SNQT--QWSHVFM 416

  Fly   445 LTSLMLTGSGILYVLFSESKLQPWNSGCHQLPDSGLKELQN 485
            ..:.....:.||..:|...|...|..     .|:.:|..:|
Worm   417 TLAGFSFVANILSFIFFTDKPAKWTE-----DDAAVKYSKN 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	109/483 (23%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	93/402 (23%)
Y4C6B.4	NP_741396.1	MFS	15..432	CDD:391944	106/469 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910