DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn6 and psmd11

DIOPT Version :9

Sequence 1:	NP_725412.2	Gene:	Rpn6 / 36638	FlyBaseID:	FBgn0028689	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_002935612.1	Gene:	psmd11 / 100492225	XenbaseID:	XB-GENE-922608	Length:	422	Species:	Xenopus tropicalis

Alignment Length:	424	Identity:	287/424 - (67%)
Similarity:	348/424 - (82%)	Gaps:	4/424 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 MAGATL--FERAQALSSVNREEQDSSLLNKLVRDQEGAENDEERIRIKEQGILQQGELYKQEGKA 80
            ||.|.:  |:|||.:...:|......|.:.:.||.:  |:|||.:|:|||.||:.|.|..:.|:|
Frog     1 MAAAAVIEFQRAQEMLVSDRAASIDILQSIVKRDIQ--ESDEEALRVKEQSILELGGLLAKTGQA 63

  Fly    81 KELADLIKVTRPFLSSISKAKAAKLVRSLVDMFLDMDAGTGIEVQLCKDCIEWAKQEKRTFLRQS 145
            .||..|:|..||||:||||||||:|||||:|:||||:|.||.||:||.:||||||.||||||||:
Frog    64 AELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKAEKRTFLRQA 128

  Fly   146 LEARLIALYFDTALYTEALALGAQLLRELKKLDDKNLLVEVQLLESKTYHALSNLPKARAALTSA 210
            |||||::|||||..|.|||.||:||||||||:|||.|||||||||||||||||||||||||||||
Frog   129 LEARLVSLYFDTKRYQEALQLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSA 193

  Fly   211 RTTANAIYCPPKVQGALDLQSGILHAADERDFKTAFSYFYEAFEGFDSVDSVKALTSLKYMLLCK 275
            ||||||||||||:|.|||:||||:|||:|:|:|||:|||||||||.||:||.||:|:||||||||
Frog   194 RTTANAIYCPPKLQAALDMQSGIIHAAEEKDWKTAYSYFYEAFEGNDSIDSPKAITALKYMLLCK 258

  Fly   276 IMLGQSDDVNQLVSGKLAITYSGRDIDAMKSVAEASHKRSLADFQAALKEYKKELAEDVIVQAHL 340
            |||...:||..|||||||:.|:||..:|:|.||:||..||||:|:.||.:||.||.:|.|:..||
Frog   259 IMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLANFEKALTDYKAELRDDPIISTHL 323

  Fly   341 GTLYDTMLEQNLCRIIEPYSRVQVAHVAESIQLPMPQVEKKLSQMILDKKFSGILDQGEGVLIVF 405
            ..|||.:|||||.|:|||:||||:.|::..|:||.|:||:|||||||||||.|||||||||||:|
Frog   324 AKLYDNLLEQNLIRVIEPFSRVQIDHISSLIKLPKPEVERKLSQMILDKKFHGILDQGEGVLIIF 388

  Fly   406 EETPVDKTYERVLETIQSMGKVVDTLYQKAKKLS 439
            :|.|||||||..|||||:|.||||:||.|||||:
Frog   389 DEPPVDKTYEAALETIQNMSKVVDSLYNKAKKLT 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn6	NP_725412.2	RPN6	18..438	CDD:227488	285/421 (68%)
Rpn6	NP_725412.2	PCI	302..406	CDD:279707	66/103 (64%)
psmd11	XP_002935612.1	RPN6	24..421	CDD:227488	277/398 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	247	1.000	Domainoid score	I2109
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2108
Inparanoid	1	1.050	559	1.000	Inparanoid score	I1087
OMA	1	1.010	-	-		QHG53498
OrthoDB	1	1.010	-	-		D1052430at2759
OrthoFinder	1	1.000	-	-		FOG0003528
OrthoInspector	1	1.000	-	-		otm48194
Panther	1	1.100	-	-	LDO	PTHR10678
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1205
SonicParanoid	1	1.000	-	-		X2408
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110