Protein Alignment jef and SP1173

DIOPT Version :8

• Sequence 1: NP_001246323.1
• Gene: jef / 36634
• FlyBaseID: FBgn0033958
• Length: 762
• Species: Drosophila melanogaster
• Sequence 2: NP_648053.1
• Gene: SP1173 / 38744
• FlyBaseID: FBgn0035710
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 830
• Identity: 156/830 - (18%)
• Similarity: 247/830 - (29%)
• Gaps: 312/830 - (37%)

  Fly   111 RELIPVKSFYFFFYAAFGSLFPLMGVYFKQMGMNPGQCGILVGMRPFVEFLSAPFWGSYADRCRQ 175
            :.||.:|...||......:|..|.......:|:|..:...:..:.|||..|.....|.:|||...
  Fly    13 KTLISLKFVVFFVITGLTALHVLHATKPLLLGLNFSEYRTITILAPFVSILGPLIAGPWADRLAA 77

  Fly   176 ------GKR--------LLLGSLACWVLFTIPLSFIRPE------AINCIER----------RNA 210
                  ||.        ||:.:.....||.:|....|.|      :..|.|.          .||
  Fly    78 KNPNTFGKTLRVLTAVFLLISAFIYAFLFAVPEVTRRGEIREPLVSFGCDETGGFLFQERCGSNA 142

  Fly   211 T-------DFVLTYTR----------------------------TKRDLSAMYEQEHLDMGTGTM 240
            |       :..:..||                            |::.....||.|.....|.::
  Fly   143 TCSRWDQKEGKINLTRCTYSCQNPKLYEPLYVAWLAEVPTVAPSTEQSSEFDYEDEGSTAVTESL 207

  Fly   241 ----------PADEALEEA---EAAHSRHKRSLLLPRIDAGISPVH------------------- 273
                      |||.|..||   |....|..|.:..|.....:.|.|
  Fly   208 RTRRDVESSDPADSAGVEAISGEVPLHRSIRQVKKPPTKVYVQPPHVCLTERNQNGEDVVKHCHA 272

  Fly   274 -----------------INFVSNYDD---------------------KYHRDY------------ 288
                             |:...:|||                     .|.:|:
  Fly   273 YTEDTTSVVMDALMGSAISQEEHYDDYEGWCQYPLEGFQCHIPEEQVNYMKDFKHYMQNDSNCKP 337

  Fly   289 ------VTPIFSSMVY-------RTPDIQKAFFLLLLVILIGEFFSAPAITLADSAVITLLGEDA 340
                  |.|.....|.       .|..:|........:.|||:.|...|:||.::|::..:.|.:
  Fly   338 MIECQVVNPYHEQSVLSDSECTNTTGSVQDTLVGYTTIRLIGDIFPMAALTLLNTAIVIAVRETS 402

  Fly   341 DKYG---HQRMFGSLGW-----GISMFLVGIALDHSTSFSNHPCGAGNKEKNYN------ICFSI 391
            :..|   .|.::|::|:     .:.:|.          |.|.|        |::      |.|.:
  Fly   403 EGRGEVCRQYVWGAIGYVVLFSPLDLFF----------FQNEP--------NHDAALVALIIFIV 449

  Fly   392 FSVLMTCAIISASKITFKYDPIDEQLAAQQQAQFVDPNKRAEEESMNQLAAQLNLPSLAVGSGSA 456
            ..||....::.|:::     |:.                 ..|...:.....|.:|..|:
  Fly   450 SFVLGAVVLLCATQM-----PLS-----------------PPEWWWHTKTGMLVVPMSAI----- 487

  Fly   457 ASGACAGGVSSFLATGHQPQPHIGAESKVFAQTAKELPEWMTVLTHFKDLKTASFLFVAWFMGFG 521
                                             .:..|| :.|||      ..|.||..::..
  Fly   488 ---------------------------------RRYTPE-ILVLT------LVSILFGTFWSS-- 510

  Fly   522 IGLIFTFLFWHLQD-----YGGTPTLFGVASVINHVSEIFAYFFSF-RLITQIGHVKVLCLGLIG 580
               |.::|:|...|     |.|             :..|...||:. :.|...||..:...||..
  Fly   511 ---IHSYLWWTFTDVDAVCYSG-------------LILILVLFFNVDKFIEYCGHSNIFIGGLAI 559

  Fly   581 NVLRFLYISYLTNPWMVLPFELMQGITHAAVWAASCSYIAHNTPKHLRASAQGVLQGIHHGLGRG 645
            .|:||..:|.....|:.:..|.::......:|.....|:.|..|:.|.|:.|.:......|||:|
  Fly   560 FVIRFTALSDAQTKWLTVIMETIEPAVIGLIWITIILYMRHAMPRKLTATGQAIAVLAFFGLGKG 624

  Fly   646 CGAIIG------GMFVTYYGTTTTFRWYGI-ACLFVLGFFIFVNFYRKEQGFISEIPVTEDPHQV 703
            .||:||      ...:.::  :.|::|..| ||:..|.:|...|       .|.....|..| |.
  Fly   625 FGALIGLARDERDPKLEFW--SCTYQWLAIVACVVALIYFGIYN-------LILAPRCTAKP-QH 679

  Fly   704 AEETSHLAPHGVPSNPIPRALSNSRLNEMNPNGGPYGTYQTTGGNLDIPG 753
            :||.            |..:.|.:..|..|.||...||....|....:.|
  Fly   680 SEEL------------ISGSASQNFGNTGNGNGAGNGTGNGNGAGASLNG 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jef	NP_001246323.1	MFS	125..187	CDD:304372	16/75 (21%)
		MFS	508..>681	CDD:119392	45/185 (24%)
		MFS_1	511..>701	CDD:284993	47/202 (23%)
SP1173	NP_648053.1	MFS	15..88	CDD:304372	19/72 (26%)
		Chromate_transp	<552..632	CDD:302665	23/79 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C296859918
eggNOG	1	0.900				E1_KOG3762
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			P	PTHR16172
RoundUp	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930