Protein Alignment CG12863 and ZCCHC4

DIOPT Version :10

• Sequence 1: NP_610973.3
• Gene: CG12863 / 36623
• FlyBaseID: FBgn0033948
• Length: 437
• Species: Drosophila melanogaster
• Sequence 2: XP_011512137.1
• Gene: ZCCHC4 / 29063
• HGNCID: 22917
• Length: 528
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 161/510 - (31%)
• Similarity: 234/510 - (45%)
• Gaps: 119/510 - (23%)

  Fly    16 DDAAPEDQHPRCEHGPTVLFNRQSQLPDQ--GYYACSAHRDSKLCNYHLPADQWKGQ-------- 70
            |.|.|.   |.|.||||:||.:.:|..::  .:|||||.||.|.||:.    ||:.:
Human    32 DPAVPA---PLCPHGPTLLFVKVTQGKEETRRFYACSACRDRKDCNFF----QWEDEKLSGARLA 89

  Fly    71 ------------TTRTALTKR-----DYPLPCRK----------P------------ANPAICD- 95
                        .:||...:|     :.||..||          |            .|.:|..
Human    90 AREAHNRRCQPPLSRTQCVERYLKFIELPLTQRKFCQTCQQLLLPDDWGQHSEHQVLGNVSITQL 154

  Fly    96 --PTLSLTALSQDKVNAQYFFDEAALNFLANQCEHIGASKVICMGAPRLHFHL--------RHKL 150
              |:..|..|...|.||||.|.:.:..||.:....:|..:|:|:|.||||..:        :..:
Human   155 RRPSQLLYPLENKKTNAQYLFADRSCQFLVDLLSALGFRRVLCVGTPRLHELIKLTASGDKKSNI 219

  Fly   151 QSFLLDLDERFAEYLGPEEFCLYNMCNNHFFYDRTPFE---QFLAGTSSDRLVIVTDPPFGCRTE 212
            :|.|||:|.|::::...:.||.|||.|:|||..:|..|   .||.....:.:::|||||||...|
Human   220 KSLLLDIDFRYSQFYMEDSFCHYNMFNHHFFDGKTALEVCRAFLQEDKGEGIIMVTDPPFGGLVE 284

  Fly   213 LISHTLRSLRKL--HNQINRLPSTPLSIFWIYPYYSANHIRQEMPELEMCEY------------- 262
            .::.|.:.|..:  ..|........|.||||:||:..:.|.|..|..:|.:|
Human   285 PLAITFKKLIAMWKEGQSQDDSHKELPIFWIFPYFFESRICQFFPSFQMLDYQAIPFFLDYRLFL 349

  Fly   263 --RINYTNHLRYTNVGKQSRFCGSPVRLFTNVPLRLLQLPPEEGYKYCQKCDCYTAKENLHCNRC 325
              :::|.||..|.: ||..| ..||||:|||:|...:.||.||||::|..|..|.:.||.||..|
Human   350 PFKVDYDNHALYKH-GKTGR-KQSPVRIFTNIPPNKIILPTEEGYRFCSPCQRYVSLENQHCELC 412

  Fly   326 GKCPSVNGQTYKHCESCDACVKPNYVHCSDCRRCTQKEGHNCSFYQTKQHCWMCGQKGHIETKCP 390
            ..|.|.:|:.:.||..|..||||:::|||.|..|...: |:|.  ..|..|::||:..|..:.||
Human   413 NSCTSKDGRKWNHCFLCKKCVKPSWIHCSICNHCAVPD-HSCE--GPKHGCFICGELDHKRSTCP 474

  Fly   391 NF-------------RKRKTN-----YTKGCLLCGKRNH-----REKRCSYRSKY 422
            |.             ::||:|     .|||    ...||     |:||.....:|
Human   475 NIATSKRANKAVRKQKQRKSNKMKMETTKG----QSMNHTSATRRKKRRERAHQY 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12863	NP_610973.3	N6-adenineMlase	109..229	CDD:463014	45/132 (34%)
		PTZ00368	299..416	CDD:173561	49/139 (35%)
ZCCHC4	XP_011512137.1	zf-GRF	38..82	CDD:480736	21/47 (45%)
		N6-adenineMlase	169..297	CDD:463014	44/127 (35%)