Protein Alignment Su(var)2-HP2 and RP1

DIOPT Version :10

• Sequence 1: NP_610972.2
• Gene: Su(var)2-HP2 / 36621
• FlyBaseID: FBgn0026427
• Length: 3257
• Species: Drosophila melanogaster
• Sequence 2: NP_006260.1
• Gene: RP1 / 6101
• HGNCID: 10263
• Length: 2156
• Species: Homo sapiens
• Alignment Length: 162
• Identity: 35/162 - (21%)
• Similarity: 53/162 - (32%)
• Gaps: 63/162 - (38%)

  Fly   211 HDMEQAFRDGFLKTDQLFLEKCE---NHHLNSG------STAVACVHHTRSQRIDVAWVGDSQAI 266
            |..|:.::.|  |.::.|..|.:   :..:::|      |....|..|.||.|       ..|.|
Human   317 HTGEKPYKCG--KCEKCFTHKGDLRSHQRIHTGEKPYKCSECDKCFTHKRSLR-------SHQRI 372

  Fly   267 LVRRNPGEGVYK-----------------PIVHPTHVASDPDERERIDREGGCVIPWNGQFRVSG 314
                :.||..||                 .|:|         ..|:..|..||    :..|...|
Human   373 ----HTGEKPYKCSECDKCFTHKRSLSIHQIIH---------TEEKPYRCSGC----DKIFNHKG 420

  Fly   315 QLAITRAIGNRFYKPYVTANPAVSLNQCTEDD 346
            .|...:.| :...|||          :|:|.|
Human   421 DLRNHQRI-HTGQKPY----------KCSECD 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-HP2	NP_610972.2	PspC_subgroup_1	<503..>842	CDD:468201
		PTZ00449	<739..1091	CDD:185628
		PTZ00108	<1132..1374	CDD:240271
		PRK05901	1624..>1822	CDD:235640
		PTZ00121	<1671..2360	CDD:173412
RP1	NP_006260.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		DCX1_RP1	36..114	CDD:340665
		DCX2_RP1	154..229	CDD:340667
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	353..375		8/32 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	666..686
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1438..1458
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1590..1621