Protein Alignment LamC and ifa-3

DIOPT Version :10

• Sequence 1: NP_001260974.1
• Gene: LamC / 36615
• FlyBaseID: FBgn0010397
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_510649.3
• Gene: ifa-3 / 181699
• WormBaseID: WBGene00002051
• Length: 581
• Species: Caenorhabditis elegans
• Alignment Length: 606
• Identity: 156/606 - (25%)
• Similarity: 277/606 - (45%)
• Gaps: 91/606 - (15%)

  Fly     4 RRVTLNTRVSRASTSTPVGG---------ASTSSRVGATSP-----TSPTRTSRQQEKEELQHLN 54
            |.||.:|:    :..||..|         ..|||.....||     .|..|..|::||:|:..||
 Worm    19 RTVTSSTQ----NYGTPASGNRVLKIVTETHTSSVASGLSPYGQGAASTIRDDREREKKEITELN 79

  Fly    55 DRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAARKLLDETAKEKAKLEI 119
            ||||.||.::|.|..:|.:|..:||:.|....:.|.::|.:||.|:..|..::.||.|:..:.|.
 Worm    80 DRLASYIGKVRFLAAQNRKLEADLNVLQSRFGKSTGSVKIMYEMEITTATNVVKETGKDHEEAEK 144

  Fly   120 DIKRLWEENDDLKPRLDKKTKEATVAENNARLYE------NRYNEVNGKYNQSLADRK--KFEDQ 176
            :|.::.::.|:|:.:.::..|..  ||:..::.|      |...|:|      |..|:  ..|::
 Worm   145 EIGKIKDQLDELRKKFEEAQKGR--AEDRLKIDELLVTLSNLEAEIN------LLKRRIALLEEE 201

  Fly   177 AKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTETRSRRQIE- 240
            ...|..||.||..:|..:|.:|:.|||.|:|.:|:..::.||:.|..:....||.:.:::...:
 Worm   202 VARLKKENFRLTSELQRVRSELDQETLLRIDNQNKVTTILEEIDFMKRGFETELKDLQAQAARDT 266

  Fly   241 ISEIDGRLSRQY-EAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQGSALAT 304
            .||     :|:| :.:|..|::::|.:|:..|..||.::|......:|.:....||.........
 Worm   267 TSE-----NREYFKNELMNSIRDIRAEYDRFMAGNRNDLESWSQIRVQEINTQTNRQNAEINHKR 326

  Fly   305 EEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRMRDEMAH 369
            :||:.:.:::..|.:|...|...|..|..::.:|...|:.:::.:...:...:|:::::|:|...
 Worm   327 DEVKRLHSQVSELKSKHAELAARNGLLEKQLEDLNYQLEDDQRSYEAALNDKDAQVRKLREECQA 391

  Fly   370 QLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESPGRPTTDSGISSNGSHLTASASSRSGRV 434
            .|.|.|.|:|.|.:||.|:..|.::|                                   .|..
 Worm   392 LLVELQMLLDTKQTLDGELKVYRRML-----------------------------------EGNS 421

  Fly   435 TPSGRRSATPGISGSSAVKRR------RTVIDESEDRTLSEYSVNAAAKGDLEIIEADVEGRFIK 493
            ..:|.|.....:..:||:...      |.|..|...||    |...:|||::.|.|...||:|:.
 Worm   422 EENGLRQLVEKVVRTSAINEEVDTETMRVVKGEHSSRT----SYQRSAKGNVSIKEVSPEGKFVI 482

  Fly   494 LHNKGTE-EINLTGWQLTR-IAGDEELAFKFSRGSKVLGGASVTIWSVDAGTAHDPPNNLVMK-- 554
            |.|...: |..|..|:|.| |.|..|:.|.|.....:....:|.|::...|.| :||..||.:
 Worm   483 LENTHRDKEEPLGDWKLKRKIDGKREIVFTFPSDYILHPVQTVKIFARGNGVA-NPPEVLVFEGD 546

  Fly   555 KKWPVANSMRSVLANADKEVR 575
            ..:....:::::|.|...|.|
 Worm   547 DTFGAGANVQTILYNNSGEER 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LamC	NP_001260974.1	Filament	45..401	CDD:459643	98/365 (27%)
		PRK13922	154..>221	CDD:473155	22/68 (32%)
		LTD	474..574	CDD:460003	30/103 (29%)
ifa-3	NP_510649.3	solA	<15..>86	CDD:236887	24/70 (34%)
		Filament	71..419	CDD:459643	98/395 (25%)
		LTD	464..570	CDD:460003	32/105 (30%)